Junction Adhesion Molecule Is a Receptor for Reovirus
Erik S. Barton,J. Craig Forrest,Jodi L. Connolly,James D. Chappell,Yuan Liu,Frederick J. Schnell,Asma Nusrat,Charles A. Parkos,Terence S. Dermody +8 more
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TLDR
Reovirus interaction with cell-surface receptors is a critical determinant of both cell-type specific tropism and virus-induced intracellular signaling events that culminate in cell death.About:
This article is published in Cell.The article was published on 2001-02-09 and is currently open access. It has received 627 citations till now. The article focuses on the topics: Tropism & Junctional Adhesion Molecule A.read more
Citations
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Journal ArticleDOI
Leukocyte transendothelial migration: a junctional affair.
TL;DR: This article will focus on the endothelial-dependent processes that coordinate transmigrations in peripheral vasculature during the inflammatory response.
Journal ArticleDOI
Junctional Adhesion Molecule A Serves as a Receptor for Prototype and Field-Isolate Strains of Mammalian Reovirus
Jacquelyn A. Campbell,Pierre Schelling,J. Denise Wetzel,Elizabeth M. Johnson,J. Craig Forrest,Greame A. R. Wilson,Michel Aurrand-Lions,Beat A. Imhof,Thilo Stehle,Terence S. Dermody +9 more
TL;DR: Antibodies specific for JAM-A were capable of inhibiting infections of HeLa cells by T1L/53, T2J/55, and T3D/ 55, demonstrating that strains of all three serotypes use JAM, A as a receptor, and little conservation in the deduced σ1 amino acid sequences among the three serotype.
Journal ArticleDOI
Role of Nucleolin in Human Parainfluenza Virus Type 3 Infection of Human Lung Epithelial Cells
TL;DR: Cell surface-expressed nucleolin was enriched on the apical cell surface domain of A549 cells, and HPIV-3 interacted with nucleolin during entry, suggesting that nucleolin expressed on the surfaces of human lung epithelial A550 cells plays an important role during HPIV -3 cellular entry.
Journal ArticleDOI
Putative Autocleavage of Outer Capsid Protein μ1, Allowing Release of Myristoylated Peptide μ1N during Particle Uncoating, Is Critical for Cell Entry by Reovirus
Amy L. Odegard,Amy L. Odegard,Kartik Chandran,Xing Zhang,John S. L. Parker,Timothy S. Baker,Max L. Nibert +6 more
TL;DR: It is found that μ1 cleavage to yield μ1N and μ1C was not required for outer capsid assembly but contributed greatly to the infectivity of the assembled particles, suggesting that hydrophobic peptide release following capsid protein autocleavage is part of a general mechanism of membrane penetration shared by several diverse nonenveloped animal viruses.
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N-Linked Glycosylation Facilitates Sialic Acid-Independent Attachment and Entry of Influenza A Viruses into Cells Expressing DC-SIGN or L-SIGN
Sarah L. Londrigan,Stuart Turville,Michelle D. Tate,Yi-Mo Deng,Andrew G. Brooks,Patrick C. Reading +5 more
TL;DR: Data indicate that human C-type lectins (DC-SIGN and L-SIGN) can mediate attachment and entry of influenza viruses independently of cell surface SA.
References
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