Junction Adhesion Molecule Is a Receptor for Reovirus
Erik S. Barton,J. Craig Forrest,Jodi L. Connolly,James D. Chappell,Yuan Liu,Frederick J. Schnell,Asma Nusrat,Charles A. Parkos,Terence S. Dermody +8 more
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TLDR
Reovirus interaction with cell-surface receptors is a critical determinant of both cell-type specific tropism and virus-induced intracellular signaling events that culminate in cell death.About:
This article is published in Cell.The article was published on 2001-02-09 and is currently open access. It has received 627 citations till now. The article focuses on the topics: Tropism & Junctional Adhesion Molecule A.read more
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Selection and characterization of a reovirus mutant with improved thermostability
Anthony J. Snyder,Pranav Danthi +1 more
TL;DR: A determinant within mammalian orthoreovirus that regulates heat resistance, disassembly kinetics, and replicative fitness is identified and capsid function is balanced for optimal replication and for spread to a new host.
Journal ArticleDOI
Modulation of Reoviral Cytolysis (II): Cellular Stemness
TL;DR: In this article , the authors characterized pathways that do not consistently modulate reoviral cytolysis and found that expression of the Yamanaka pluripotency factors may be associated with regulating reovirus selectivity.
Dissertation
Effect of Probiotic Consortium on Level and Mechanism of Intestine Function.
TL;DR: Data presented in this study suggest that DFM increase metabolic efficiency via changes in intestinal physiology and metabolism, especially when compared to the traditional feed supplement prophylactic, salinomycin.
Journal ArticleDOI
Gain of function studies on predicted host receptors for white spot virus.
TL;DR: In this article , protein-protein docking is applied to evaluate the interaction of VP28 trimeric extracellular region with four host (Penaeus monodon) receptors reported earlier, Rab7 GTPase, glucose transporter 1 (PmGLUT1), C-type lectin and calreticulin.
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The human neuronal receptor NgR1 bridges reovirus capsid proteins to initiate infection
D. M. Sutherland,M. Strebl,Melanie Koehler,Olivia L. Welsh,Olivia L. Welsh,Xinzhe Yu,Liya Hu,R. dos Santos Natividade,Jonathan J. Knowlton,Gwen M. Taylor,R. Moreno,P. Woerz,Z. L. Lonergan,Pavithra Aravamudhan,Pavithra Aravamudhan,Camila Guzman-Cardozo,Camila Guzman-Cardozo,David Alsteens,Zhengjia Wang,B.V.V. Prasad,Thilo Stehle,Terence S. Dermody,Terence S. Dermody +22 more
TL;DR: In this article, the authors defined the affinity of interaction between virus and receptor, determined the structure of the virus-receptor complex, and identified residues in the receptor required for virus binding and infection.
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