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Journal ArticleDOI

Non-specific low back pain

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TLDR
Two treatment strategies are currently used, a stepped approach beginning with more simple care that is progressed if the patient does not respond, and the use of simple risk prediction methods to individualise the amount and type of care provided.
About
This article is published in The Lancet.The article was published on 2017-02-18. It has received 1687 citations till now. The article focuses on the topics: Low back pain & Disease burden.

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Citations
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Clinical assessment and patient-reported outcome measures in low-back pain - a survey among primary health care physiotherapists.

TL;DR: The findings show that physiotherapists working in primary health care use clinical testing in LBP to a great extent, while various patient-reported outcome measures are used to a low-to-very-low extent.
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MiR-202-3p regulates interleukin-1β-induced expression of matrix metalloproteinase 1 in human nucleus pulposus.

TL;DR: It is suggested that miR-202-3p is an important regulator of MMP-1 in human nucleus pulposus and may contribute to the development of intervertebral disc degeneration.
Journal ArticleDOI

Behavioral Compensations and Neuronal Remodeling in a Rodent Model of Chronic Intervertebral Disc Degeneration

TL;DR: A clinically relevant behavioral phenotype in a rodent model of chronic intervertebral disc degeneration is described which provides a means to map sensory neuron changes to a single affected lumbar interverTEbral disc.
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Proteomic signature of the murine intervertebral disc.

TL;DR: Characterization of the protein composition of healthy intervertebral disc tissue is an important first step in identifying cellular processes and pathways disrupted during aging or disease progression.
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MRI of non-specific low back pain and/or lumbar radiculopathy: do we need T1 when using a sagittal T2-weighted Dixon sequence?

TL;DR: In patients with non-specific low back pain or lumbar radiculopathy, spine MRI in the sagittal plane could be limited to a single FSE T2-weighted Dixon sequence, hereby reducing the acquisition time.
References
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Journal ArticleDOI

Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

Theo Vos, +689 more
- 22 Aug 2015 - 
TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as mentioned in this paper, the authors estimated the quantities for acute and chronic diseases and injuries for 188 countries between 1990 and 2013.
Journal ArticleDOI

CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016

TL;DR: This guideline is intended to improve communication about benefits and risks of opioids for chronic pain, improve safety and effectiveness of pain treatment, and reduce risks associated with long-term opioid therapy.
Journal ArticleDOI

CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016.

TL;DR: This guideline is intended to improve communication between clinicians and patients about the risks and benefits of opioid therapy for chronic pain, improve the safety and effectiveness of pain treatment, and reduce the risks associated with long-term opioid therapy, including opioid use disorder, overdose, and death.
Journal ArticleDOI

Grading the severity of chronic pain.

TL;DR: A Guttman scale analysis showed that pain intensity and disability measures formed a reliable hierarchical scale and may be useful when a brief ordinal measure of global pain severity is required.
Related Papers (5)

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Theo Vos, +778 more
- 16 Sep 2017 -