C
Charles A. Dinarello
Researcher at University of Colorado Denver
Publications - 1073
Citations - 152254
Charles A. Dinarello is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Interleukin & Cytokine. The author has an hindex of 190, co-authored 1058 publications receiving 139668 citations. Previous affiliations of Charles A. Dinarello include University of Guadalajara & Pennsylvania State University.
Papers
More filters
Journal ArticleDOI
Proinflammatory Cytokines in Heart Disease
TL;DR: The potential for anticytokine-based therapies in treating heart disease is great and two orally effective agents, the IL-1β-converting enzyme inhibitor and the mitogen-activating protein kinase p38 inhibitor, are currently being investigated in clinical trials.
Journal ArticleDOI
Interleukin-1 as a mediator of fatigue in disease: a narrative review
Megan E. Roerink,Marieke E. van der Schaaf,Charles A. Dinarello,Charles A. Dinarello,Hans Knoop,Hans Knoop,Jos W. M. van der Meer +6 more
TL;DR: This narrative review aims to improve the understanding of fatigue in both inflammatory and non-inflammatory illnesses, which could help develop strategies to treat fatigue more effectively.
Journal ArticleDOI
Recent advances in cytokines, Cytokine Receptors and Signal Transduction
TL;DR: The Fifth Annual Conference of the International Cytokine Society was held on November 9-13, 1997 at Lake Tahoe, Nevada, with a tradition of exciting talks and posters, presenting significant advances in the understanding of the cytokine world.
Journal Article
The induction of interleukin-1 in humans and its metabolic effects.
TL;DR: The dissociation of acute-phase and catabolic responses may reflect the magnitude of the stimulus; higher levels of interleukin-1 may initiate catabolicResponses; other mediators such as the counterregulatory hormones may direct theCatabolic responses that occur after injury and sepsis.
Journal ArticleDOI
Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes
Rogier J. L. Stuyt,Mihai G. Netea,Teunis B.H. Geijtenbeek,Bart Jan Kullberg,Charles A. Dinarello,Jos W. M. van der Meer +5 more
TL;DR: IL‐18 selectively up‐regulates the expression of ICAM‐1 on monocytes, and this contributes to the proinflammatory effects of this cytokine.