C
Charles A. Dinarello
Researcher at University of Colorado Denver
Publications - 1073
Citations - 152254
Charles A. Dinarello is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Interleukin & Cytokine. The author has an hindex of 190, co-authored 1058 publications receiving 139668 citations. Previous affiliations of Charles A. Dinarello include University of Guadalajara & Pennsylvania State University.
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Journal ArticleDOI
Resistant Behçet disease responsive to anakinra.
Journal ArticleDOI
Alarmins: Feel the Stress.
TL;DR: This article suggests a novel activity of these molecules as central initiators of sterile inflammation in response to nonlethal stress, a function the authors denote “stressorins,” and highlights the role of posttranslational modifications of stressorins as key regulators of their activity.
Journal Article
Induction of circulating IL-1 receptor antagonist by IFN treatment.
H Tilg,James W. Mier,Wolfgang Vogel,Walter E. Aulitzky,Christian J. Wiedermann,Edouard Vannier,Ch. Huber,Charles A. Dinarello +7 more
TL;DR: The induction of IL-1Ra may contribute to the antiviral, anti-inflammatory, and antiproliferative effects of IFN.
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The natural interleukin-1 receptor antagonist in tem and preterm parturition
Roberto Romero,Waldo Sepulveda,Moshe Mazor,Francisco Brandt,David B. Cotton,Charles A. Dinarello,Murray D. Mitchell +6 more
TL;DR: Amniotic fluid contains the highest interleukin-1 receptor antagonist concentrations detected in any biologic fluid to date and exogenous anticytokine agents may be of value in the treatment of preterm labor.
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Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function.
A. Mario Q. Marcondes,Andrew J. Mhyre,Derek L. Stirewalt,Soo-Hyun Kim,Charles A. Dinarello,H. Joachim Deeg +5 more
TL;DR: It is proposed that IL-32 is a marrow stromal marker that distinguishes patients with myelodysplastic syndrome and chronic myelomonocytic leukemia and may be a therapeutic target.