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Charles A. Dinarello

Researcher at University of Colorado Denver

Publications -  1073
Citations -  152254

Charles A. Dinarello is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Interleukin & Cytokine. The author has an hindex of 190, co-authored 1058 publications receiving 139668 citations. Previous affiliations of Charles A. Dinarello include University of Guadalajara & Pennsylvania State University.

Papers
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Journal ArticleDOI

Activated platelets induce endothelial secretion of interleukin-8 in vitro via an interleukin-1-mediated event

Gilles Kaplanski, +5 more
- 15 May 1993 - 
TL;DR: Observations show that activated platelets induce IL-8 secretion via membrane-associated IL-1 activity, and provide a novel relationship between coagulation and inflammation that could be relevant to several diseases.
Journal Article

The differential effects of human leukocyte pyrogen/lymphocyte-activating factor, T cell growth factor, and interferon on human natural killer activity.

Roy A. Dempsey, +6 more
- 01 Dec 1982 - 
Journal Article

The effects of interleukin 1 on human B cell activation and proliferation.

R J Falkoff, +5 more
- 01 Aug 1983 - 
TL;DR: The importance of accessory cell factors for the initial rounds of B cell proliferation depends on the strength of the initial slg-mediated activation signal, and when this is strong, the response is maximal and independent of accessory cells or accessory cell Factors.
Journal ArticleDOI

Increased Levels of Interleukin-1 Are Detected in Nasal Secretions of Volunteers during Experimental Rhinovirus Colds

David Proud, +5 more
- 01 May 1994 - 
TL;DR: Investigation of the potential involvement of interleukin-1 in the pathogenesis of experimental rhinovirus colds found that most activity in lavages from infected subjects was IL-1 beta, consistent with the hypothesis thatIL-1 could contribute to the pathogenic of rhinOVirus infections.
Journal ArticleDOI

Innate immune cell activation and epigenetic remodeling in symptomatic and asymptomatic atherosclerosis in humans in vivo

Siroon Bekkering, +11 more
- 01 Nov 2016 - 
TL;DR: Circulating monocytes of patients with symptomatic, but not asymptomatic, atherosclerosis have a pro-inflammatory phenotype and increased expression of glycolytic enzymes, associated with epigenetic remodeling at the level of histone methylation.