C
Charles A. Dinarello
Researcher at University of Colorado Denver
Publications - 1073
Citations - 152254
Charles A. Dinarello is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Interleukin & Cytokine. The author has an hindex of 190, co-authored 1058 publications receiving 139668 citations. Previous affiliations of Charles A. Dinarello include University of Guadalajara & Pennsylvania State University.
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Journal ArticleDOI
Circulating lymphokine levels in the chronic fatigue syndrome.
Journal ArticleDOI
Genetic susceptibility markers in Danish patients with type 1 (insulin-dependent) diabetes : evidence for polygenecity in man
Flemming Pociot,Kjersti S. Rønningen,Regine Bergholdt,T. Lorenzen,Jesper Johannesen,Ke Ye,Charles A. Dinarello,Jørn Nerup +7 more
TL;DR: No significant differences between familial and sporadic cases were found within the MHC region, and the type 1 diabetics in both groups of patients were negative for both DQA1*0301-DQB 1*0302 and DQa1*0501- DQB1*0201 genotypes.
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Understanding human immune function using the resources from the Human Functional Genomics Project
Mihai G. Netea,Leo A. B. Joosten,Yang Li,Vinod Kumar,Marije Oosting,Sanne P. Smeekens,Martin Jaeger,Rob ter Horst,Melanie Schirmer,Melanie Schirmer,Hera Vlamakis,Hera Vlamakis,Richard A. Notebaart,Norman Pavelka,Norman Pavelka,Raul Aguirre-Gamboa,Morris A. Swertz,Rahajeng N. Tunjungputri,Wouter van de Heijden,Eric A. Franzosa,Eric A. Franzosa,Aylwin Ng,Aylwin Ng,Daniel B. Graham,Daniel B. Graham,Kara G. Lassen,Kara G. Lassen,Kiki Schraa,Romana T. Netea-Maier,Jan Smit,Quirijn de Mast,Frank L. van de Veerdonk,Bart Jan Kullberg,Cees J. Tack,Inge van de Munckhof,Joost H.W. Rutten,Jacqueline van der Graaf,Lude Franke,Marten H. Hofker,Iris Jonkers,Mathieu Platteel,Astrid Maatman,Jingyuan Fu,Alexandra Zhernakova,Jos W. M. van der Meer,Charles A. Dinarello,Charles A. Dinarello,André J. A. M. van der Ven,Curtis Huttenhouwer,Curtis Huttenhouwer,Hans J. P. M. Koenen,Irma Joosten,Ramnik J. Xavier,Ramnik J. Xavier,Cisca Wijmenga +54 more
TL;DR: Understanding human immune function using the resources from the Human Functional Genomics Project to improve understanding of immune regulation in patients with multiple sclerosis.
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Identification of Amino Acid Residues Critical for Biological Activity in Human Interleukin-18
Soohyun Kim,Tania Azam,Daniela Novick,Do-Young Yoon,Leonid L. Reznikov,Philip Bufler,Menachem Rubinstein,Charles A. Dinarello +7 more
TL;DR: It is revealed that Glu-42 and Lys-89 are critical amino acid residues for the integrity of IL-18 structure and are important for binding to cell surface receptors, for signal transduction, and for neutralization byIL-18BP.
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Effect of Indomethacin on Increased Resistance to Bacterial Infection and on Febrile Responses Induced by Muramyl Dipeptide
TL;DR: Indomethacin alone stimulated resistance to bacterial infection and, under appropriate conditions, had a strong synergistic effect when combined with free or conjugated MDP.