NIH Image to ImageJ: 25 years of image analysis
TLDR
The origins, challenges and solutions of NIH Image and ImageJ software are discussed, and how their history can serve to advise and inform other software projects.Abstract:
For the past 25 years NIH Image and ImageJ software have been pioneers as open tools for the analysis of scientific images. We discuss the origins, challenges and solutions of these two programs, and how their history can serve to advise and inform other software projects.read more
Citations
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Ultraconserved Enhancers Are Required for Normal Development.
Diane E. Dickel,Athena R. Ypsilanti,Ramón Pla,Yiwen Zhu,Iros Barozzi,Brandon J. Mannion,Yupar S. Khin,Yoko Fukuda-Yuzawa,Ingrid Plajzer-Frick,Catherine S. Pickle,Elizabeth Lee,Anne N. Harrington,Quan T. Pham,Tyler H. Garvin,Momoe Kato,Marco Osterwalder,Jennifer A. Akiyama,Veena Afzal,John L.R. Rubenstein,Len A. Pennacchio,Len A. Pennacchio,Len A. Pennacchio,Axel Visel,Axel Visel,Axel Visel +24 more
TL;DR: It is shown that ultraconserved enhancers are required for normal development and indicates that remarkably strong sequence conservation likely results from fitness deficits that appear subtle in a laboratory setting.
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Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation.
Katherine A. Overmyer,Charles R. Evans,Nathan Qi,Catherine E. Minogue,Joshua J. Carson,Christopher J. Chermside-Scabbo,Lauren G. Koch,Steven L. Britton,David J. Pagliarini,Joshua J. Coon,Charles F. Burant +10 more
TL;DR: Using metabolomic and proteomic profiling, it is shown that HCR efficiently oxidize fatty acids and branched-chain amino acids, sparing glycogen and reducing accumulation of short- and medium-chain acylcarnitines.
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A Carbon Nanotube Reporter of miRNA Hybridization Events In Vivo.
Jackson D. Harvey,Prakrit V. Jena,Hanan A. Baker,Hanan A. Baker,Gül H. Zerze,Ryan M. Williams,Thomas V. Galassi,Thomas V. Galassi,Daniel Roxbury,Jeetain Mittal,Daniel A. Heller,Daniel A. Heller +11 more
TL;DR: An engineered carbon-nanotube-based sensor capable of real-time optical quantification of hybridization events of microRNA and other oligonucleotides is reported, which allows for detection via single-molecule sensor elements and for multiplexing by using multiple nanotube chiralities.
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Evolution of Acid-Sensing Olfactory Circuits in Drosophilids
Lucia L. Prieto-Godino,Raphael Rytz,Steeve Cruchet,Benoîte Bargeton,Liliane Abuin,Ana F. Silbering,Vanessa Ruta,Matteo Dal Peraro,Matteo Dal Peraro,Richard Benton +9 more
TL;DR: This work links olfactory ecology to structural and regulatory genetic changes influencing nervous system anatomy and function to show that D. sechellia exhibits derived odor-evoked attraction and physiological sensitivity to the abundant Morinda volatile hexanoic acid.
Journal ArticleDOI
Promoting Roles of Melatonin in Adventitious Root Development of Solanum lycopersicum L. by Regulating Auxin and Nitric Oxide Signaling.
Dan Wen,Biao Gong,Shasha Sun,Shiqi Liu,Xiufeng Wang,Min Wei,Fengjuan Yang,Yan Li,Qinghua Shi +8 more
TL;DR: Results suggest that elevated NO levels resulting from inhibited GSNOR activity and auxin signaling were involved in the MT-induced ARF in tomato plants, which can be applied in basic research and breeding.
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