Bowling Green State University

About: Bowling Green State University is a education organization based out in Bowling Green, Ohio, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 8315 authors who have published 16042 publications receiving 482564 citations. The organization is also known as: BGSU.

Cationic 5,10,15,20-Tetrakis(N-methylpyridinium-4-yl)porphyrin Fully Intercalates at 5‘-CG-3‘ Steps of Duplex DNA in Solution†

Abstract: The interaction of 5,10,15,20-tetrakis(N-methylpyridinium-4-yl)porphyrin (T4MPyP4+) with the oligonucleotide DNA duplex [d(GCACGTGC)]2 was studied by two-dimensional 1H NMR spectroscopy, optical absorbance, circular dichroism, and molecular dynamics simulation employing particle mesh Ewald methods. T4MPyP4+ is one of the largest aromatic molecules for which intercalative binding to DNA has been proposed, although this has been called into question by recent X-ray crystallographic work [Lipscomb et al. (1996) Biochemistry 35, 2818−2823]. T4MPyP4+ binding to [d(GCACGTGC)]2 produced a single set of (mostly) upfield-shifted DNA resonances in slow exchange with the resonances of the free DNA. Intra- and intermolecular NOEs observed in the complex showed that the porphyrin intercalates at the central 5‘-CG-3‘ step of the DNA duplex without disrupting the flanking base pairs. Absorption and circular dichroism spectra of the complex also support intercalative binding. Molecular dynamics simulations (using explici...

Moving toward a grand theory of development: in memory of Esther Thelen.

Abstract: This paper is in memory of Esther Thelen, who passed away while President of the Society for Research in Child Development. A survey of Esther Thelen's career reveals a trajectory from early work on simple movements like stepping, to the study of goal-directed reaching, to work on the embodiment of cognition, and, ultimately, to a grand theory of development—dynamic systems theory. Four central concepts emerged during her career: (1) a new emphasis on time; (2) the proposal that behavior is softly assembled from the interaction of multiple subsystems; (3) the embodiment of perception, action, and cognition; and (4) a new respect for individuality. Esther Thelen communicated these ideas to scientists and practitioners alike, so the ultimate benefactors of her work were children.

Examining corporate reputation judgments with generalizability theory.

Abstract: The researchers used generalizability theory to examine whether reputation judgments about corporations function in a manner consistent with contemporary theory in the corporate-reputation literature. University professors (n = 86) of finance, marketing, and human resources management made repeated judgments about the general reputations of highly visible American companies. Minimal variability in the judgments is explained by items, time, persons, and field of specialization. Moreover, experts from the different specializations reveal considerable agreement in how they weigh different aspects of corporate performance in arriving at their global reputation judgments. The results generally support the theory of the reputation construct and suggest that stable estimates of global reputation can be achieved with a small number of items and experts.

Case Management and Recidivism of Mentally Ill Persons Released From Jail

Abstract: Objective: The study tested the hypothesis that case management provided to mentally ill offenders both in jail and after release from jail would reduce their recidivism. Methods: A total of 261 inmates of the Lucas County (Toledo, Ohio) jail who were diagnosed with a mental disorder were tracked for three years after their release. The relationships between recidivism and diagnostic, demographic, and case management variables were examined through event history analysis. Results: Recidivism was associated with age, employment, previous arrests, and receipt of community-based case management. Receipt of jail-based case management, although not directly related to recidivism, significantly increased the probability of receiving community-based case management. Receipt of community case management was significantly associated with a lower probability of rearrest and a longer period before rearrest. Conclusions: This study found hopeful signs that expanding access to case management, both inside and outside jail, will help mentally ill people live in their communities and stay out of jail. (Psychiatric Services 49:1330‐1337, 1998) ple leaving jail. They found no significant difference in recidivism between recipients of the three treatments. The study reported here examined the relationship between the intensity of case management and the criminal recidivism of 261 mentally ill persons released from jail and tracked for three years. We hypothesized that after demographic, criminal history, and diagnostic variables were controlled, recidivism would be inversely related to the amount of case management received both inside and outside jail. Methods Study site