Journal ArticleDOI
Changes in miRNA levels of sperm and small extracellular vesicles of seminal plasma are associated with transient scrotal heat stress in bulls.
Maíra Bianchi Rodrigues Alves,Rubens Paes de Arruda,Leonardo Batissaco,L. N. Garcia-Oliveros,Vitor Hugo Guilger Gonzaga,Vinícius José Moreira Nogueira,F. S. Almeida,S. C. C. Pinto,Gabriella Mamede Andrade,Felipe Perecin,Juliano Coelho da Silveira,Eneiva Carla Carvalho Celeghini +11 more
TLDR
The findings suggest that miR-126-5p was possibly trafficked between sEVs and sperm and provide new insights on the mechanism by which sperm acquire miRNAs in the last stages of spermatogenesis and sperm maturation in cattle.About:
This article is published in Theriogenology.The article was published on 2021-02-01. It has received 16 citations till now. The article focuses on the topics: Sperm & Semen.read more
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Journal ArticleDOI
Extracellular vesicles in seminal fluid and effects on male reproduction. An overview in farm animals and pets.
TL;DR: Extracellular vesicles (EVs) are lipid bilayer nanoveicles released by most functional cells to body fluids, containing bioactive molecules, mainly proteins, lipids, and nucleic acids having actions at target cells.
Journal ArticleDOI
Extracellular vesicles in seminal fluid and effects on male reproduction. An overview in farm animals and pets
TL;DR: Extracellular vesicles (EVs) are lipid bilayer nanoveicles released by most functional cells to body fluids, containing bioactive molecules, mainly proteins, lipids, and nucleic acids having actions at target cells as mentioned in this paper .
Journal ArticleDOI
Spermatozoa and seminal plasma small extracellular vesicles miRNAs as biomarkers of boar semen cryotolerance.
Ana Carolina Pedrosa,Mariana Andrade Torres,Diego V. Alkmin,Jorge E.P. Pinzon,Simone Maria Massami Kitamura Martins,Juliano Coelho da Silveira,André Furugen Cesar de Andrade +6 more
TL;DR: In this article, the miRNAs present in sperm cells and small extracellular vesicles (EVs) from seminal plasma of raw boar ejaculates can predict high quality ejaculates after underwent the freeze-thaw process.
Journal ArticleDOI
GH Overexpression Alters Spermatic Cells MicroRNAome Profile in Transgenic Zebrafish.
William Borges Domingues,Tony Silveira,Leandro S. Nunes,Eduardo B. Blödorn,Augusto Schneider,Carine Dahl Corcine,Antonio Sergio Varela Junior,Izani Bonel Acosta,Mateus Tavares Kütter,Gonzalo Greif,Carlos Robello,Danillo Pinhal,Luis Fernando Marins,Vinicius Farias Campos +13 more
TL;DR: In this article, the authors reported a significant increase in body weight of transgenic zebrafish males along with associated reduced sperm motility and other kinetic parameters in comparison to the non-transgenic group.
Journal ArticleDOI
Responses of Sperm Mitochondria Functionality in Animals to Thermal Stress: The Mitigating Effects of Dietary Natural Antioxidants.
Sameh A. Abdelnour,Ayman A. Swelum,Ramya A. Sindi,Rasha A Barkat,Norhan E. Khalifa,Ahmed Al Amin,Ali Ali El-Raghi,Vincenzo Tufarelli,Caterina Losacco,Mohamed E. Abd El-Hack +9 more
TL;DR: The potential influences of HS on sperm function through reduction of ATP synthesis yield, mitochondrial activity, mitochondrial protein contents and mitochondrial enzymes which involves the interference of mitochondrial remodeling in sperm of animals are highlighted.
References
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Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
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Fish,Miguel Flores-Bellver,András Försönits,Annie Frelet-Barrand,Fabia Fricke,Fabia Fricke,Gregor Fuhrmann,Susanne Gabrielsson,Ana Gámez-Valero,Chris Gardiner,Kathrin Gärtner,Raphael Gaudin,Raphael Gaudin,Yong Song Gho,Bernd Giebel,Caroline Gilbert,Mario Gimona,Ilaria Giusti,Deborah C.I. Goberdhan,André Görgens,André Görgens,Sharon M. Gorski,David W. Greening,Julia Christina Gross,Alice Gualerzi,Gopal N. Gupta,Dakota Gustafson,Aase Handberg,Reka A. Haraszti,Paul Harrison,Hargita Hegyesi,An Hendrix,Andrew F. Hill,Fred H. Hochberg,Karl F. Hoffmann,Beth Holder,Harry Holthöfer,Baharak Hosseinkhani,Guoku Hu,Yiyao Huang,Yiyao Huang,Veronica Huber,Stuart Hunt,Ahmed Ibrahim,Tsuneya Ikezu,Jameel M. Inal,Mustafa Isin,Alena Ivanova,Hannah K Jackson,Søren Jacobsen,Steven M. Jay,Muthuvel Jayachandran,Guido Jenster,Lanzhou Jiang,Suzanne M. Johnson,Jennifer Jones,Ambrose Jong,Tijana Jovanovic-Talisman,Stephanie M. Jung,Raghu Kalluri,Shin Ichi Kano,Sukhbir Kaur,Yumi Kawamura,Yumi Kawamura,Evan T. 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Carmen Martinez,Vilma R. Martins,Mathilde Mathieu,Suresh Mathivanan,Marco Maugeri,Lynda K. McGinnis,Mark J. McVey,David G. Meckes,Katie Meehan,Inge Mertens,Inge Mertens,Valentina R. Minciacchi,Andreas Möller,Malene Jørgensen,Aizea Morales-Kastresana,Jess Morhayim,François Mullier,Maurizio Muraca,Luca Musante,Veronika Mussack,Dillon C. Muth,Kathryn H. Myburgh,Tanbir Najrana,Muhammad Nawaz,Irina Nazarenko,Irina Nazarenko,Peter Nejsum,Christian Neri,Tommaso Neri,Rienk Nieuwland,Leonardo Nimrichter,John P. Nolan,Esther N. M. Nolte-‘t Hoen,Nicole Noren Hooten,Lorraine O'Driscoll,Tina O'Grady,Ana O'Loghlen,Takahiro Ochiya,Martin Olivier,Alberto Ortiz,Luis A. Ortiz,Xabier Osteikoetxea,Ole Ostegaard,Ole Ostegaard,Matias Ostrowski,Jaesung Park,D. Michiel Pegtel,Héctor Peinado,Francesca Perut,Michael W. Pfaffl,Donald G. Phinney,Bartijn C. H. Pieters,Ryan C. Pink,David S. Pisetsky,Elke Pogge von Strandmann,Iva Polakovicova,Ivan K. H. Poon,Bonita H. Powell,Ilaria Prada,Lynn Pulliam,Lynn Pulliam,Peter J. Quesenberry,Annalisa Radeghieri,Robert L. Raffai,Robert L. Raffai,Stefania Raimondo,Janusz Rak,Marcel I. Ramirez,Marcel I. Ramirez,Graça Raposo,Morsi S. Rayyan,Neta Regev-Rudzki,Franz Ricklefs,Paul D. Robbins,David D. Roberts,Silvia C Rodrigues,Eva Rohde,Sophie Rome,Kasper M.A. Rouschop,Aurelia Rughetti,Ashley E. Russell,Paula Saa,Susmita Sahoo,Edison Salas-Huenuleo,Catherine Sánchez,Julie A. Saugstad,Meike J. Saul,Raymond M. Schiffelers,Raphael Schneider,Tine Hiorth Schøyen,Aaron Scott,Eriomina Shahaj,Shivani Sharma,Olga Shatnyeva,Faezeh Shekari,Ganesh Vilas Shelke,Ashok K. Shetty,Kiyotaka Shiba,Pia Siljander,Andreia M. Silva,Agata Skowronek,Orman L. Snyder,Rodrigo Pedro Soares,Barbara W Sódar,Carolina Soekmadji,Carolina Soekmadji,Javier Sotillo,Philip D. Stahl,Willem Stoorvogel,Shannon L. 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Wheelock,Zoltán Wiener,Leonie Witte,Joy Wolfram,Joy Wolfram,Joy Wolfram,Angeliki Xagorari,Patricia Xander,Jing Xu,Xiaomei Yan,María Yáñez-Mó,María Yáñez-Mó,Hang Yin,Yuana Yuana,Valentina Zappulli,Jana Zarubova,Jana Zarubova,Vytautas Žėkas,Jian ye Zhang,Zezhou Zhao,Lei Zheng,Alexander R. Zheutlin,Antje M. Zickler,Pascale Zimmermann,Pascale Zimmermann,Angela M. Zivkovic,Davide Zocco,Ewa K. Zuba-Surma +417 more
TL;DR: The MISEV2018 guidelines include tables and outlines of suggested protocols and steps to follow to document specific EV-associated functional activities, and a checklist is provided with summaries of key points.
Journal ArticleDOI
MAPK signal pathways in the regulation of cell proliferation in mammalian cells.
Wei Zhang,Hui Tu Liu +1 more
TL;DR: MAPK families are discussed for their functions and cooperation with other signal pathways in regulation of cell proliferation.
Journal ArticleDOI
Confocal Imaging–Guided Laser Ablation of Basal Cell Carcinomas: An Ex Vivo Study
Journal ArticleDOI
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
TL;DR: Current understanding of the composition and regulation of the Hippo pathway is summarized, and how cell polarity and cell adhesion proteins inform the role of this pathway in organ size control and regeneration is discussed.