Journal ArticleDOI
Pharmaceutical Applications of Cyclodextrins. 1. Drug Solubilization and Stabilization
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TLDR
The effects of substitution on various cyclodextrins properties and the forces involved in the drug-cyclodextrin complex formation are discussed, and methods which are useful in the optimization of complexation efficacy are reviewed.About:
This article is published in Journal of Pharmaceutical Sciences.The article was published on 1996-10-01. It has received 2124 citations till now. The article focuses on the topics: Cyclodextrin & Inclusion compound.read more
Citations
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Journal ArticleDOI
Improving the solubility of ampelopsin by solid dispersions and inclusion complexes
TL;DR: The solubility and dissolution rates of AMP were significantly increased by solid dispersions and cyclodextrin complexes as well as their physical mixtures.
Journal ArticleDOI
Poly-cyclodextrin and poly-paclitaxel nano-assembly for anticancer therapy
Ran Namgung,Yeong Mi Lee,Jihoon Kim,Yuna Jang,Byung Heon Lee,In San Kim,In San Kim,Pandian Sokkar,Young Min Rhee,Allan S. Hoffman,Allan S. Hoffman,Won Jong Kim +11 more
TL;DR: This novel targeted nano-assembly exhibits significant antitumour activity in a mouse tumour model and provides knowledge for the development of advanced anticancer drug delivery.
Journal ArticleDOI
Nanosponges: a novel class of drug delivery system--review.
TL;DR: Tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner, which allows the use of these systems effectively for drugs with poor solubility.
Journal ArticleDOI
The formation of host-guest complexes between surfactants and cyclodextrins.
Artur J.M. Valente,Olle Söderman +1 more
TL;DR: The influence on the thermodynamic properties of CD-surfactant association is reviewed by highlighting the effect of different surfactant architectures (single tail, double-tailed, gemini and bolaform), with special emphasis on cationic surfactants.
Journal ArticleDOI
Exploring versatile applications of cyclodextrins: an overview
Neha Sharma,Ashish Baldi +1 more
TL;DR: A review of cyclodextrins and their applications in various industrial products, technologies, analytical and chemical processes and recent industrial advancements by extensively literature search on various scientific databases, Google an as discussed by the authors.
References
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Journal ArticleDOI
The Determination of Enzyme Dissociation Constants
Hans Lineweaver,Dean Burk +1 more
TL;DR: On the basis of the assumed theory the rate of the observed reaction is directly proportional to the concentration of the enzyme-substrate compound, where (E:l = (ES).
Book
Handbook of Pharmaceutical Excipients
TL;DR: The Handbook of Pharmaceutical Excipients is internationally recognised as the authoritative source of information on pharmaceutical excipients giving a comprehensive guide to uses, properties and safety.
Journal ArticleDOI
Cyclodextrin Inclusion Compounds in Research and Industry
TL;DR: As cyclodextrins catalyze several chemical reactions they and their functionalized derivatives provide useful enzyme models and can be used to advantage in the production of pharmaceuticals, pesticides, foodstuffs, and toilet articles.
Journal ArticleDOI
Stability of Protein Pharmaceuticals
TL;DR: Current methodology to stabilize proteins is presented, including additives, excipients, chemical modification, and the use of site-directed mutagenesis to produce a more stable protein species.
Book
Cyclodextrins in Pharmacy
TL;DR: The present study focused on the development and application of Cyclodextrin Inclusion Compounds in Various Drug Formulations, as well as their applications in Pharmaceutical Applications and Legal Aspects.