Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Incorporating simvastatin/poloxamer 407 hydrogel into 3D-printed porous Ti6Al4V scaffolds for the promotion of angiogenesis, osseointegration and bone ingrowth.
Hao Liu,Wei Li,Can Liu,Jie Tan,Hong Wang,Bao Hai,Hong Cai,Huijie Leng,Zhongjun Liu,Chunli Song +9 more
TL;DR: In conclusion, incorporating simvastatin/poloxamer 407 hydrogel into pTi scaffolds significantly improves neovascularization, osseointegration and bone ingrowth.
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Enhanced Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells by a Functionalized Silk Fibroin Hydrogel for Bone Defect Repair
TL;DR: This work suggests that SF could be easily tailored with bioactive peptide gelators to afford bioactive hydrogels with favorable microenvironments for tissue regeneration applications.
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Injectable conducting interpenetrating polymer network hydrogels from gelatin-graft-polyaniline and oxidized dextran with enhanced mechanical properties
TL;DR: This work presents a simple approach to prepare injectable conductive interpenetrating polymer network (IPN) hydrogels with enhanced mechanical properties and biocompatibility as bioactive biomaterials, which have great potential for drug delivery and tissue engineering.
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Current Developments in 3D Bioprinting for Tissue and Organ Regeneration–A Review
TL;DR: This paper focuses on the applications of 3D bioprinting technology on construction of various representative tissue and organs, including skin, cardiac, bone and cartilage etc, and attempts to highlight the steps involved in each of those tissues/organs printing.
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Biocompatible and Biodegradable Bioplastics Constructed from Chitin via a “Green” Pathway for Bone Repair
Meng He,Xiaolan Wang,Zhenggang Wang,Lingyun Chen,Yao Lu,Xinjiang Zhang,Mei Li,Zhongming Liu,Yu Zhang,Hong Xia,Lina Zhang +10 more
TL;DR: Novel chitin based plastics were successfully fabricated by changing the shape and aggregation state structure of chit in hydrogels through drying under a negative pressure, which led to a plastic deformation.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.