Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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A novel pathway to produce biodegradable and bioactive PLGA/TiO2 nanocomposite scaffolds for tissue engineering: Air-liquid foaming.
TL;DR: The novel method utilized in this work generated porous viable tissue without using any inorganic solvent or porogen can be a promising candidate in further treatment of orthopedic patients effectively.
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The promotion of bone regeneration through CS/GP-CTH/antagomir-133a/b sustained release system.
Fusong Jiang,Fuli Yin,Yiwei Lin,Wenyang Xia,Lihui Zhou,Chenhao Pan,Nan Wang,Haojie Shan,Zubin Zhou,Xiaowei Yu +9 more
TL;DR: It is demonstrated that CTH nanoparticles could facilitate continuous dosing of antagomiR133a/b, which can promote osteogenic differentiation and calcium deposition and osteogenic specific gene expression were enhanced in vitro.
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Tissue Engineering and Three-Dimensional Printing in Periodontal Regeneration: A Literature Review
Simon Raveau,Fabienne Jordana +1 more
TL;DR: The process, the materials and designs, the key advantages and prospects of 3D bioprinting are highlighted, providing new ideas for tissue regeneration.
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Synthesis and characterization of bioactive glass coated forsterite scaffold for tissue engineering applications
TL;DR: In this article, a simple way to improve the compressive strength and bioactivity of forsterite scaffolds by coating them with bioactive glass was proposed, and the obtained scaffolds provided good mechanical support with remarkable bioactivity so they could be used as tissue engineering scaffolds for load bearing applications.
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Fabrication and detection of tissue engineered bone aggregates based on encapsulated human ADSCs within hybrid calcium alginate/bone powder gel-beads in a spinner flask
Kedong Song,Yanfei Yang,Lili Xu,Jiaxin Tian,Jiangli Fan,Zeren Jiao,Shihao Feng,Hong Wang,Yiwei Wang,Ling Wang,Tianqing Liu +10 more
TL;DR: In this paper, the authors used hybrid gel-beads to encapsulate human ADSCs, which were then used as an in-vitro niche-like matrix to treat bone diseases.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.