Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Evaluation of Hyaluronic Acid/Agarose Hydrogel for Cartilage Tissue Engineering Biomaterial
Joo Hee Choi,Jin Su Kim,Won Kyung Kim,Wonchan Lee,Namyeong Kim,Cheol Ui Song,Jun Jae Jung,Jeong Eun Song,Gilson Khang +8 more
TL;DR: The composite biomaterial exhibited applicability for cartilage tissue engineering and the in vitro study of the cell-laden HA/AG hydrogel displayed potential for cartritis tissue engineering in the future.
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Ligament Regenerative Engineering: Braiding Scalable and Tunable Bioengineered Ligaments Using a Bench-Top Braiding Machine
TL;DR: The development of a bench-top braiding machine that can be used in research laboratories to investigate the fabrication of bioengineered ACLs that are much stronger than current ACL grafts is described.
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Injectable composites based on biosilicate® and alginate: handling and in vitro characterization
Paulo Roberto Gabbai-Armelin,Paulo Roberto Gabbai-Armelin,D. Alves Cardoso,Edgar Dutra Zanotto,Oscar Peitl,Sander C.G. Leeuwenburgh,John A. Jansen,Ana Claudia Muniz Renno,J.J.J.P van den Beucken +8 more
TL;DR: The material properties of injectable Biosilicate®/alginate formulations seem suitable for bone regenerative applications, for which future studies should aim at biological evaluation in animal experimental models.
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Icariin-releasing 3D printed scaffold for bone regeneration
Luca M. Possati,Erica Rowan +1 more
TL;DR: In this paper , a 3D printed polycaprolactone (PCL) and nano-hydroxyapatite (nHAP) composite is used for bone regeneration.
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Mineralized collagen scaffolds fabricated with amniotic membrane matrix increase osteogenesis under inflammatory conditions.
Marley J. Dewey,Eileen M. Johnson,Simona T Slater,Derek J. Milner,Matthew B. Wheeler,Brendan A.C. Harley +5 more
TL;DR: It is suggested that a mineralized collagen–amnion scaffold may provide a beneficial environment to aid craniomaxillofacial bone repair, especially in the course of defects presenting significant inflammatory complications.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.