Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Fabrication of 3D Printed PCL/PEG Polyblend Scaffold Using Rapid Prototyping System for Bone Tissue Engineering Application
TL;DR: The findings suggest that the presence of small pores on the scaffolds can be used as an effective tool for improving implant cellular interaction and can be considered useful for bone tissue engineering applications to improve human health.
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Micro porosity analysis in additive manufactured NiTi parts using micro computed tomography and electron microscopy
Saeed Khademzadeh,Saeed Khademzadeh,Simone Carmignato,Nader Parvin,Filippo Zanini,Paolo Francesco Bariani +5 more
TL;DR: In this article, a micro direct metal deposition process was used to fabricate porous NiTi parts, and the effect of process parameters on formation and distribution of micro pores was analyzed using micro computed tomography and scanning electron microscopy.
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Bone tissue engineering in osteoporosis
Franz Jakob,Regina Ebert,Anita Ignatius,Takashi Matsushita,Yoshinobu Watanabe,Juergen Groll,Heike Walles +6 more
TL;DR: Standard operating procedures for ex vivo tissue engineering of bone will be developed in the near future, tailored for compromised conditions like vitamin D and sex hormone deficiencies, cellular deficits and high production of regeneration inhibitors, as they are prevalent in osteoporosis and in higher age.
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A combined nanostructure constructed by graphene and boron nitride nanotubes reinforces ceramic scaffolds
TL;DR: In this paper, a combined nanostructure was constructed by two-dimensional graphene and one-dimensional boron nitride nanotubes (BNNTs), in which the long and straight BNNTs sandwiched the broad and thin graphene sheets, thereby efficiently inhibiting the aggregation of graphene.
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Polyurethane foam scaffold as in vitro model for breast cancer bone metastasis.
Valentina Angeloni,Nicola Contessi,Cinzia De Marco,Serena Bertoldi,Maria Cristina Tanzi,Maria Grazia Daidone,Silvia Farè +6 more
TL;DR: The suitability of a porous polyurethane foam, synthesized using an appropriate formulaton, is proved in mimicking the bone tissue microenvironment and in reproducing the metastatic colonization derived from human breast cancer, particularly evidencing the devastating effects on the bone extracellular matrix caused by metastatic spreading.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.