Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Engineered Extracellular Vesicles: Tailored-Made Nanomaterials for Medical Applications.
TL;DR: This review will explore various engineering strategies that could promote EVs scalability and therapeutic effectiveness beyond their native utility and highlight the current state-of-the-art EV-engineering techniques with discussion of opportunities and obstacles.
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Emerging nanostructured materials for musculoskeletal tissue engineering
TL;DR: The microenvironment of the extracellular matrix in musculoskeletal tissues is introduced and the nanostructured materials currently used in musculuskeletal tissue engineering including natural polymers, synthetic polymers and inorganic materials are summarized.
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Electrospun nanofiber blend with improved mechanical and biological performance.
Anderson Oliveira Lobo,Samson Afewerki,Samson Afewerki,Mirian Michele Machado de Paula,Paria Ghannadian,Fernanda Roberta Marciano,Fernanda Roberta Marciano,Yu Shrike Zhang,Yu Shrike Zhang,Thomas J. Webster,Ali Khademhosseini +10 more
TL;DR: Findings appear promising for the use of these electrospun scaffolds, based on the combination of polymers used here for numerous orthopedic applications, and those ultrathin fiber characteristics improved hFOB functions.
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Effects of pore distribution and chemistry on physical, mechanical, and biological properties of tricalcium phosphate scaffolds by binder-jet 3D printing
Dongxu Ke,Susmita Bose +1 more
TL;DR: In this article, a 3D printed MgO/ZnO-TCP scaffold was shown to enhance the surface roughness and osteoblast proliferation of TCP scaffolds.
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Three-dimensional bioprinting of cell-laden constructs with polycaprolactone protective layers for using various thermoplastic polymers.
TL;DR: A novel bioprinting method to use various synthetic polymers in fabrication of cell-printed constructs with remarkable improvement in cellular activities in the printed constructs with PCL layers was observed compared with the construct without PCL.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.