Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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3D bioactive composite scaffolds for bone tissue engineering.
Gareth Turnbull,Jon Clarke,Frederic Picard,Frederic Picard,Philip Riches,Luanluan Jia,Fengxuan Han,Bin Li,Wenmiao Shu +8 more
TL;DR: This review will consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers, hydrogels, metals, ceramics and bio-glasses in BTE.
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Biomimetic porous scaffolds for bone tissue engineering
TL;DR: An overview of the design of ideal biomimetic porous scaffolds for bone tissue engineering is presented, and concepts and techniques including the production of a hierarchical structure on both the macro- and nano-scales, the adjustment of biomechanical properties through structural alignment and chemical components, and the control of the biodegradability of the scaffold and its by-products are discussed.
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Advancing biomaterials of human origin for tissue engineering
Fa-Ming Chen,Xiaohua Liu +1 more
TL;DR: An exploration of the structural, mechanical, biochemical and biological information present in native human tissue for bioengineering applications is focused on to provide inspiration for the design of future biomaterials.
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Scaffold Design for Bone Regeneration
TL;DR: This focus of this review is on the evolution of these scaffolds as bone graft substitutes in the process of recreating the bone tissue microenvironment, including biochemical and biophysical cues.
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Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications
TL;DR: It was found that inclusion of alloying elements such as Al, Mn, Ca, Zn and rare earth elements provides improved corrosion resistance to Mg alloys and surface modification is a promising approach to improve the performance of Mg-based biomaterials for orthopaedic applications.
References
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A biodegradable porous composite scaffold of PGA/β-TCP for bone tissue engineering
Hong Cao,Noboru Kuboyama +1 more
TL;DR: In this article, three-dimensional (3D) porous composite scaffolds of PGA/β-TCP (in 1:1 and 1:3 weight ratios) were fabricated using the solvent casting and particulate leaching method.
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Oxygen gradients in tissue-engineered PEGT/PBT cartilaginous constructs: measurement and modeling.
Jos Malda,Jos Malda,Jeroen Rouwkema,Dirk E. Martens,E. P. le Comte,F.K. Kooy,Johannes Tramper,C.A. van Blitterswijk,Jens Uwe Riesle +8 more
TL;DR: The ability to measure and predict local oxygen tensions offers new opportunities to obtain more insight in the relation between oxygen tension and chondrogenesis.
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Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds.
TL;DR: In vitro cell-materials interaction studies confirmed that the addition of SiO(2) and ZnO to the scaffolds facilitated faster cell proliferation when compared to pure TCP scaffolds, showing increased mechanical strength as well as increased cellular proliferation.
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The influence hydroxyapatite nanoparticle shape and size on the properties of biphasic calcium phosphate scaffolds coated with hydroxyapatite-PCL composites.
TL;DR: The developed composite scaffolds possessed superior physical, mechanical, elastic and biological properties rendering them potentially useful for bone tissue regeneration.
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Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering.
TL;DR: The results show that bioresorbable 3D‐printed TCP scaffolds have great potential in tissue engineering applications for bone tissue repair and regeneration.