Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Preparation Strategies for Mg-alloys for Biodegradable Orthopaedic Implants and Other Biomedical Applications: A Review
G. Chandra,A. Pandey +1 more
TL;DR: This review focuses on preparation techniques employed in development of Mg – alloys for biodegradable orthopaedic implants (fracture fixation implants) and can essentially be split into: material optimization, processing techniques, and surface modifications.
Journal ArticleDOI
A Novel Silver Bioactive Glass Elicits Antimicrobial Efficacy Against Pseudomonas aeruginosa and Staphylococcus aureus in an ex Vivo Skin Wound Biofilm Model.
TL;DR: Evidence is provided that BgAg elicits potent antimicrobial effects against planktonic and single-species biofilms, with beneficial effects on the host tissue response, which is shown to benefit the host response to biofilm infection.
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Osteogenic efficacy of strontium hydroxyapatite micro-granules in osteoporotic rat model:
TL;DR: The therapeutical potential of micro-granular Strontium incorporated Hydroxyapatite scaffolds becomes relevant, especially as bone void fillers in osteoporotic cases of tumor resection or trauma.
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An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites
Mónica S. Ventura Ferreira,Christian Bergmann,Isabelle Bodensiek,Kristina Peukert,Jessica Abert,Rafael Kramann,Rafael Kramann,Paul Kachel,Björn Rath,Stephan Rütten,Ruth Knüchel,Benjamin L. Ebert,Benjamin L. Ebert,Horst Fischer,Tim H. Brümmendorf,Rebekka K. Schneider,Rebekka K. Schneider +16 more
TL;DR: The development and characterization of a tissue-engineered BM model comprising of cellular and structural components with increased potential for hematopoietic recapitulation at ectopic transplantation sites is reported, which is a powerful tool to explore the regulatory mechanisms of hematopsilage stem and progenitor cells for a better understanding of he matopoiesis in health and disease.
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Novel bone-mimetic nanohydroxyapatite/collagen porous scaffolds biomimetically mineralized from surface silanized mesoporous nanobioglass/collagen hybrid scaffold: Physicochemical, mechanical and in vivo evaluations.
TL;DR: By using surface silanized mesoporous NBG hybridization with collagen fibrillar network, this work successfully introduced a new approach for developing novel bone-mimetic nanohydroxyapatite/collagen hybrid scaffolds that possess significant potential for bone tissue regeneration.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.