Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Substance P/dexamethasone‐encapsulated PLGA scaffold fabricated using supercritical fluid process for calvarial bone regeneration
TL;DR: SP‐ and Dex‐encapsulated scaffolds made by the supercritical CO2 foaming method could be a good treatment modality to treat critical bone defects without cell transplantation by recruiting autologous stem cells and forming new bone tissues.
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Bioactive borophosphosilicate-polycaprolactone hybrid biomaterials via a non-aqueous sol gel process
TL;DR: In this article, a non-aqueous sol-gel process was utilized to prepare novel class II hybrid biomaterials based on functionalized polycaprolactone (PCL) diol and borophosphosilicate glass (BPSG) as potential scaffold material for bone tissue engineering applications.
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Preparation Strategies for Mg-Alloys for Biodegradable Orthopaedic Implants and Other Biomedical Applications: A Review
TL;DR: In this article , a review of preparation techniques employed in development of Mg-based alloys for biodegradable orthopaedic implants (fracture fixation implants) is presented.
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In-situ growth of silica nano-protrusions on halloysite nanotubes for interfacial reinforcement in polymer/halloysite scaffolds
TL;DR: In this paper, SiO2 nano-protrusions were in-situ grown on HNT via the hydrolysis of tetraethoxysilane (TEOS) and the polycondensation of its intermediates with the surface O-H groups of HNT.
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Bioinspired double polysaccharides-based nanohybrid scaffold for bone tissue engineering.
Fan Tiantang,Jingdi Chen,Panpan Pan,Zhang Yujue,Yimin Hu,Xiaocui Liu,Xuetao Shi,Qiqing Zhang,Qiqing Zhang +8 more
TL;DR: In vitro tests indicated that the hybrid nanostructured chitosan/chondroitin sulfate/hydroxyapatite in situ composite scaffold improved the growth of the osteoblasts and was promising for bone repair application in bone tissue engineering.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.