Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Functionalized scaffolds to enhance tissue regeneration.
TL;DR: The development and trends of functional scaffolding biomaterials including electrically conducting hydrogels and nanocomposites of hydroxyapatite (HA) and bioactive glasses (BGs) with various biodegradable polymers are summarized.
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Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications
TL;DR: The important roles of biomolecules in the synthesis of NCaPs are focused on, which are expected to guide the design and controlled synthesis ofNCaPs and discuss their current research trends and future prospects.
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3D printing of concentrated alginate/gelatin scaffolds with homogeneous nano apatite coating for bone tissue engineering
TL;DR: Focus on alginate/gelatin scaffolds with uniform nano apatite coating, which had 2-fold higher Young's modulus and significantly stimulated the proliferation and osteogenic differentiation of rat bone marrow stem cells.
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Hydroxyapatite from fish scale for potential use as bone scaffold or regenerative material.
Weeraphat Pon-On,Panan Suntornsaratoon,Narattaphol Charoenphandhu,Jirawan Thongbunchoo,Nateetip Krishnamra,I. Ming Tang +5 more
TL;DR: The results confirm that the bio-materials derived from fish scale (FSHA) are biologically better than the chemically synthesized HA and have the potential for use as a bone scaffold or as regenerative materials.
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Biomimetic, Osteoconductive Non-mulberry Silk Fiber Reinforced Tricomposite Scaffolds for Bone Tissue Engineering
Prerak Gupta,Mimi Adhikary,Joseph Christakiran M,Manishekhar Kumar,Nandana Bhardwaj,Biman B. Mandal +5 more
TL;DR: The fabricated tricomposite scaffolds supported enhanced cellular viability and function (ALP activity) for both MG63 osteosarcoma and human bone marrow stem cells (hBMSCs) as compared to pure silk scaffolds without fiber or HA addition.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.