Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Synthesis of shape memory electroconductive polyurethane with self-healing capability as an intelligent biomedical scaffold for bone tissue engineering
Alireza Shaabani,Roya Sedghi +1 more
TL;DR: In this paper, the synthesis of electroactive self-healing polyurethane scaffolds (PUAT) with shape memory ability based on aniline trimer and disulfide bonds is reported.
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Applying extrusion-based 3D printing technique accelerates fabricating complex biphasic calcium phosphate-based scaffolds for bone tissue regeneration
TL;DR: In this article , the authors discuss materials and methods utilized for BCP robocasting and discuss possible strategies and opportunities for the use of BCP toward injured bone regeneration, including commercialization and marketing approach, post-processing steps, clinical applications, in-vitro and invivo evaluations beside the biological responses.
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3D Printing of Porous Scaffolds for Medical Applications
Ablah Aljohani,Salil Desai +1 more
TL;DR: In this paper, the authors used finite element analysis to study the relationship between structure, porosity and mechanical strength of the scaffolds and the results indicated that diamond unit-cell pattern had the highest stress and displacement.
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Orthobiologics with phytobioactive cues: A paradigm in bone regeneration.
TL;DR: A bird's eye view of different strategies used in bone healing, mechanisms involved and future direction of advancements using phytobioactives and orthobiologics is provided.
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Bioactive silica nanoparticles with calcium and phosphate for single dose osteogenic differentiation.
TL;DR: The novel bioactive SiNPs-CaP nanomaterials are synthesized in a simple and fast manner and show the ability to promote osteogenic differentiation after a single dose administration, independently from external osteogenic inducers, showing great potential as carriers in bone tissue engineering applications.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.