Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Book ChapterDOI
Structural polymer biomaterials
TL;DR: This chapter begins with a discussion of the fundamental concepts related to structural properties, followed by an introduction of a number of structural biopolymers.
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Bioactivity of surface tethered Osteogenic Growth Peptide motifs
Silvia Panseri,Laura Russo,Monica Montesi,Francesca Taraballi,Carla Cunha,Maurilio Marcacci,Laura Cipolla +6 more
TL;DR: New evidence of the role of OGP in osteogenesis and new insights into different OGP motifs able to act as best ligands for the design of innovative bioactive materials for osteogenesis promotion and regenerative medicine applications are presented.
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The influence of amorphous macrodiol, diisocyanate type and l-ascorbic acid modifier on chemical structure, morphology and degradation behavior of polyurethanes for tissue scaffolds fabrication
TL;DR: In this paper, the bulk synthesis and characterization of polyurethanes obtained with the use of cyclic 4,4′-methylene bis(cyclohexyl isocyanate) (HMDI) or linear 1,6-hexamethylene diisocyanates (HDI), amorphous α,ω-dihydroxy(ethylene-butylene adipate) macrodiol (PEBA), 1,4-butandiol (BDO) chain extender and dibutyltin dilaurate (DBT
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Toward stronger robocast calcium phosphate scaffolds for bone tissue engineering: A mini-review and meta-analysis
Quyang Liu,Wen Feng Lu,Wei Zhai +2 more
TL;DR: In this article, the current state of knowledge and existing research on robocasting of calcium phosphate scaffolds are presented, and a meta-analysis of the compressive strength of these scaffolds is provided.
Book ChapterDOI
Ceramic devices for bone regeneration: Mechanical and clinical issues and new perspectives
David Marchat,Eric Champion +1 more
TL;DR: In this article, a personalized approach based on tissue engineering in association with the implementation and development of versatile additive manufacturing technologies appears very promising achievement of this approach must be based on the use of cell mechanics and growth in the design of "bioinstructive" ceramic scaffolds.
References
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Journal ArticleDOI
Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI
Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal ArticleDOI
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
Journal ArticleDOI
The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.