Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Preparation and characterization of gelatin/α-TCP/SF biocomposite scaffold for bone tissue regeneration
TL;DR: The new biocomposite scaffold composed of gelatin/α-TCP (tricalcium phosphate)/SF (silk-fibroin) (GTS) which has enhanced mechanical strength and high level of cellular activity will be one of highly potential biomaterials to be used in bone regeneration.
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Manufacturing, characterization and applications of lightweight metallic foams for structural applications: Review
TL;DR: In this paper, the fabrication and characterization of metal foams for bone implant applications is discussed and a review of various biomaterials, fabrication methods of metal foam, aluminium and its alloy foam and characterization techniques are reviewed in present work.
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Bone-like apatite formation on manganese-hydroxyapatite coating formed on Ti-6Al-4V alloy by plasma electrolytic oxidation
TL;DR: In this paper, a bone-like apatite formation on manganese-hydroxyapatite (Mn-HA) coatings formed on Ti-6Al-4V by plasma electrolytic oxidation (PEO) has been investigated by several techniques.
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Sequential dual-drug delivery of BMP-2 and alendronate from hydroxyapatite-collagen scaffolds for enhanced bone regeneration.
Dongtak Lee,Maierdanjiang Wufuer,Insu Kim,Tae Hyun Choi,Byung Jun Kim,Hyo Gi Jung,Byoungjun Jeon,Gyudo Lee,Ok-Hee Jeon,Hak Chang,Dae Sung Yoon +10 more
TL;DR: In this paper, the authors demonstrated the synergistic effect of two bioactive molecules, bone morphogenic protein-2 (BMP-2) and alendronate (ALN), by releasing them in a sequential manner.
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Exosomes Derived from Stem Cells from the Apical Papilla Promote Dentine-Pulp Complex Regeneration by Inducing Specific Dentinogenesis.
Xueying Zhuang,Ling-Li Ji,Huan Jiang,Yao Liu,Xuemei Liu,Jing Bi,Weidong Zhao,Zhenjiang Ding,Xu Chen +8 more
TL;DR: The use of exosomes derived from dental stem cells could comprise a potential therapeutic approach for dentine-pulp complex regeneration in REPs.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.