Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:Â
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
Citations
More filters
Journal ArticleDOI
3D Bioplotting of Gelatin/Alginate Scaffolds for Tissue Engineering: Influence of Crosslinking Degree and Pore Architecture on Physicochemical Properties
TL;DR: The crosslinked gelatin/alginate scaffolds showed a good potential to encapsulate cells or drugs and markedly improved the stability and mechanical strength of the hydrogel scaffolds.
Journal ArticleDOI
Polymeric Systems for Bioprinting.
TL;DR: A review of recent bioprinting innovations, such as increasing architectural complexity and cell viability in heterogeneous tissue constructs, which allow for the investigation of biological questions that could not be addressed before.
Journal ArticleDOI
Evaluation of the osteoinductive potential of a bio-inspired scaffold mimicking the osteogenic niche for bone augmentation
Silvia Minardi,Bruna Corradetti,Francesca Taraballi,Monica Sandri,Jeffrey L. Van Eps,Fernando J. Cabrera,Bradley K. Weiner,Anna Tampieri,Ennio Tasciotti +8 more
TL;DR: A high level of structural mimicry by the scaffold to the composition and structure of human osteogenic niche that translated to faster and more efficient osteoinduction in vivo is confirmed, suggesting such a biomaterial may have great utility in future clinical applications where bone regeneration is required.
Journal ArticleDOI
Low-Temperature Additive Manufacturing of Biomimic Three-Dimensional Hydroxyapatite/Collagen Scaffolds for Bone Regeneration.
Kaifeng Lin,Shu He,Yue Song,Chunmei Wang,Gao Yi,Junqin Li,Peng Tang,Zheng Wang,Long Bi,Guoxian Pei +9 more
TL;DR: A low-temperature robocasting method was employed to print biomimic 3D scaffolds for bone regeneration using a routine collagen-hydroxyapatite (CHA) composite material, which is too viscous to be printed via normal 3D printing methods at low temperature.
Journal ArticleDOI
Biodegradable metallic bone implants
TL;DR: This review summarizes the current research status onBiodegradable metals as bone implants, including their biodegradability, mechanical properties, and biocompatibility.
References
More filters
Journal ArticleDOI
Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI
Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal ArticleDOI
Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
Journal ArticleDOI
The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.