Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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3D printing of biomaterials
TL;DR: A broad overview of the field of 3D-printed biomaterials along with a few specific applications can be found in this paper to assist the reader in obtaining an understanding of the current state of the art.
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Nanocomposite hydrogels for tissue engineering applications
TL;DR: Nanocomposite hydrogels, with its advantages of high mechanical property and some unique properties, have emerged as the most versatile and innovative technology, which provides a new opportunity as a unique tool for fabricating hydrogel with excellent properties in tissue engineering.
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Biomaterials and bioengineering tomorrow’s healthcare
Sumrita Bhat,Ashok Kumar +1 more
TL;DR: Micro-needles have the potential to overcome the limitations of conventional needles and are being studied for the delivery of drugs at different location in human body and there is a huge advancement in the area of scaffold fabrication which has improved the potentiality of tissue engineering.
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Production and characterization of chitosan/gelatin/β-TCP scaffolds for improved bone tissue regeneration
Inês Raquel Tavares Serra,R. Fradique,Mariana C. Vallejo,Tiago Ruivo Correia,Sónia P. Miguel,Ilídio J. Correia +5 more
TL;DR: 3D structures produced by freeze-drying are bioactive and biocompatible, allow cell internalization and show antimicrobial activity against Staphylococcus aureus, make these 3D structures as potential candidates for being used on the bone tissue regeneration, since they promote cell adhesion and proliferation and also prevent biofilm development at their surfaces.
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Biomaterials for the Delivery of Growth Factors and Other Therapeutic Agents in Tissue Engineering Approaches to Bone Regeneration.
TL;DR: This review considers the various biomaterial carriers under investigation to promote bone regeneration and a survey of the literature where various pharmacological approaches and molecular targets are considered as future strategies to promote more rapid and mature bone regeneration.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.