Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Shape-memory materials and their clinical applications
Raana Sarvari,Peyman Keyhanvar,Samira Agbolaghi,Mohammad Sadegh Gholami Farashah,Amirhouman Sadrhaghighi,Mohammad Nouri,Laila Roshangar +6 more
TL;DR: Shape-memory characteristics shed light on materials science and open horizons for accessing to unconventional functions in material categories subsuming metals, polymers, and ceramics as discussed by the authors...
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Macrophages enhance mesenchymal stem cell osteogenesis via down-regulation of reactive oxygen species.
TL;DR: It is suggested that targeting MSC-macrophage interaction is an effective strategy for regulating stem cell fate and facilitating bone regeneration.
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Facile fabrication and characterization on alginate microfibres with grooved structure via microfluidic spinning.
TL;DR: Alginate fibres, with topological structure, are candidates for wound dressing or the engineering tissue scaffolds, and exhibited an increasing tendency as the concentration of alginate solution increased.
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Net Shape Nonwoven: a novel technique for porous three-dimensional nonwoven hybrid scaffolds
Martin Hild,Ronny Brünler,Maria Jäger,Ezzeding Laourine,Laura Scheid,Danka Haupt,Dilbar Aibibu,Chokri Cherif,Thomas Hanke +8 more
TL;DR: The novel chitosan-hybrid scaffolds provide proper conditions for adhesion, proliferation and differentiation of the seeded human bone marrow stromal cells, proving that they are suitable for usage in hard-tissue regeneration.
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Interconnected porosity analysis by 3D X-ray microtomography and mechanical behavior of biomimetic organic-inorganic composite materials.
S. Alonso-Sierra,Rodrigo Velázquez-Castillo,Beatriz Millan-Malo,R. Nava,Lauro Bucio,Alejandro Manzano-Ramírez,H. Cid-Luna,Eric M. Rivera-Muñoz +7 more
TL;DR: The pore size distribution obtained could be capable to allow cell penetration, internal tissue in-growth, vascular incursion and nutrient supply and this material has tremendous potential for use as a replacement of bone tissue or in the manufacture and molding of prosthesis with desired shapes.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.