Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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New perspectives: In-situ tissue engineering for bone repair scaffold
TL;DR: The preparation needs, in-situ preparation methods, functional bone repair scaffold and the application of functional scaffold composite in in-Situ tissue engineering are described.
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Nanocellulose/bioactive glass cryogels as scaffolds for bone regeneration.
F.V. Ferreira,Lucas Pereira Lopes de Souza,Thaís Maria da Mata Martins,João Henrique Lopes,Bruno D. Mattos,Marcos Mariano,Ivanei Ferreira Pinheiro,Thalita Marcolan Valverde,Sébastien Livi,José Angelo Camilli,Alfredo M. Goes,Rubia F. Gouveia,Liliane M. F. Lona,Orlando J. Rojas +13 more
TL;DR: CNF are made bioactive for bone formation through a simple and scalable strategy that achieves highly interconnected 3D networks and Ion release is found critical to enhance the production of the bone morphogenetic protein 2 from cells within the fractured area, thus accelerating the in vivo bone repair.
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3D Printing for Tissue Engineering
TL;DR: This review will cover several approaches that have advanced the field of 3D printing through novel fabrication methods of tissue engineering constructs and discuss the applications of synthetic and natural materials for3D printing facilitated tissue fabrication.
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Fabrication of PLLA/β-TCP nanocomposite scaffolds with hierarchical porosity for bone tissue engineering
TL;DR: The nanocomposite scaffolds supported MG-63 osteoblast proliferation, penetration, and ECM deposition, indicating the potential of PLLA/β-TCP nanocomPOSITE scaffolds with hierarchical porosity for bone tissue engineering applications.
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Gelatin-alginate-cerium oxide nanocomposite scaffold for bone regeneration.
Shiv Dutt Purohit,Hemant Singh,Rakesh Bhaskar,Indu Yadav,Chia-Fu Chou,Mukesh Kumar Gupta,Narayan Chandra Mishra +6 more
TL;DR: It could be stated that NC incorporated GA nanocomposite scaffold has vital importance for applications in bone tissue-engineering in future regenerative therapies.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.