Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Journal ArticleDOI
Osteogenic activity of nanonized pearl powder/poly (lactide-co-glycolide) composite scaffolds for bone tissue engineering.
Yueh-Lung Yang,Ching-Hsien Chang,Ching-Cheng Huang,Wenny Mei-Wen Kao,Wei-Chung Liu,Hsia-Wei Liu +5 more
TL;DR: This study indicates that the efficiency of nanonized pearl powders in bone cell differentiation are certainly different from that of proteins.
Journal ArticleDOI
Electron Microscopy for 3D Scaffolds-Cell Biointerface Characterization.
Donata Iandolo,Fabrizio A. Pennacchio,Valentina Mollo,Domenico Rossi,David Dannhauser,Bianxiao Cui,Róisín M. Owens,Francesca Santoro +7 more
TL;DR: Using scanning electron microscopy coupled with a focused ion beam (SEM/FIB) for the characterization of cell interactions with 3D scaffolds obtained by different fabrication techniques is reported for the first time, showing the capability of the developed approach to preserve and finely resolve scaffold–cell interfaces.
Book ChapterDOI
Ceramics in Bone Grafts and Coated Implants
TL;DR: In this chapter, different aspects of bioceramics are discussed from fundamental science to applications, and several ASTM/ISO standards and requirements for regulatory organizations are presented for ceramic materials toward orthopedic applications.
Journal ArticleDOI
Titanium alloy modified with anti-biofouling zwitterionic polymer to facilitate formation of bio-mineral layer.
Miku Nishida,Tadashi Nakaji-Hirabayashi,Hiromi Kitano,Yoshiyuki Saruwatari,Kazuyoshi Matsuoka +4 more
TL;DR: The zwitterionic polymer-modified surfaces not only showed enhanced mineralization clusters creation and growth, but they were also highly non-responsive to biologically derived materials such as proteins and cells, making it possible to easily form highly pure and rigid hydroxyapatite layers on Ti alloy surfaces without the incorporation of organic molecules.
Journal ArticleDOI
Influence of microwave processing and sintering temperature on the structure and properties of Sr/Zr doped hydroxyapatite
TL;DR: In this paper, the effect of different sintering techniques and temperatures on the structural and morphological properties of as-synthesized samples was investigated using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).
References
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Journal ArticleDOI
Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI
Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
Journal ArticleDOI
The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.