Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Synthesis and 3D Interconnected Nanostructured h-BN-Based Biocomposites by Low-Temperature Plasma Sintering: Bone Regeneration Applications.
Chandkiram Gautam,Dibyendu Chakravarty,Amarendra Gautam,Chandra Sekhar Tiwary,Cristiano F. Woellner,Cristiano F. Woellner,Vijay Kumar Mishra,Naseer Ahmad,Sehmus Ozden,Sujin P. Jose,Santoshkumar Biradar,Robert Vajtai,Ritu Trivedi,Douglas S. Galvao,Pulickel M. Ajayan +14 more
TL;DR: The composite showed significant effect on cell viability/proliferation and shows a high mineralized nodule formation over the control, which suggests its use as a possible osteogenic agent in bone formation.
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Electrospun polycaprolactone/gelatin/bioactive glass nanoscaffold for bone tissue engineering
TL;DR: The results of mechanical test revealed that by adding bioactive glass to scaffolds, the ultimate tensile strength and Young's modulus increase about two folds.
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Development of Arabinoxylan-Reinforced Apple Pectin/Graphene Oxide/Nano-Hydroxyapatite Based Nanocomposite Scaffolds with Controlled Release of Drug for Bone Tissue Engineering: In-Vitro Evaluation of Biocompatibility and Cytotoxicity against MC3T3-E1
Wafa Shamsan Al-Arjan,Muhammad U. Khan,Samina Nazir,Saiful Izwan Abd Razak,Mohammed Rafiq Abdul Kadir +4 more
TL;DR: These novel nanocomposites can serve as potential future biomaterials to repair defected bone with the load-bearing application, and in bone tissue engineering.
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Multimaterial Segmented Fiber Printing for Gradient Tissue Engineering
Luis Diaz-Gomez,Brandon T. Smith,Panayiotis D. Kontoyiannis,Sean M. Bittner,Anthony J. Melchiorri,Antonios G. Mikos +5 more
TL;DR: A segmented three-dimensional printing methodology is introduced to create multimaterial porous scaffolds with discrete gradients and controlled distribution of compositions useful in tissue engineering.
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Development of functionalized multi-walled carbon nanotube-based polysaccharide–hydroxyapatite scaffolds for bone tissue engineering
Rajendiran Rajesh,Y. Dominic Ravichandran,M. Jeevan Kumar Reddy,Sung Hun Ryu,A.M. Shanmugharaj +4 more
TL;DR: New tricomponent composite scaffolds with high porosity and ability to promote cell proliferation of the MG 63 cell line for bone regeneration are ascertained that they can be used as promising materials in bone tissue engineering.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.