Recent advances in bone tissue engineering scaffolds.
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TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Mesenchymal Stromal/Stem Cells in Regenerative Medicine and Tissue Engineering.
TL;DR: The history of MSC research from the initial discovery of their multipotency to the more recent recognition of their perivascular identity in vivo and their extraordinary capacity for immunomodulation and angiogenic signaling is summarized.
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Degradable conductive self-healing hydrogels based on dextran-graft-tetraaniline and N-carboxyethyl chitosan as injectable carriers for myoblast cell therapy and muscle regeneration
TL;DR: A series of injectable electroactive biodegradable hydrogels with rapid self-healing ability composed of N-carboxyethyl chitosan (CECS) and dextran-graft-aniline oligomers are synthesized and demonstrated their potential application as cell delivery vehicles for skeletal muscle regeneration.
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Current Concepts in Scaffolding for Bone Tissue Engineering.
Toktam Ghassemi,Azadeh Shahroodi,Mohammad H Ebrahimzadeh,Alireza Mousavian,Jebraeel Movaffagh,Ali Moradi +5 more
TL;DR: This paper reviews studies on bone tissue engineering from the biomaterial point of view in scaffolding and concludes that physiochemical modifications in terms of porosity, mechanical strength, cell adhesion, biocompatibility, cell proliferation, mineralization and osteogenic differentiation are required.
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Bone physiology as inspiration for tissue regenerative therapies.
TL;DR: A systematic parallelization of fundamental well-established biology of bone, updated and recent advances on the understanding of biological phenomena occurring in native and injured tissue, and critical discussion of how individual aspects have been translated into tissue regeneration strategies using biomaterials and other tissue engineering approaches are suggested.
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Recent developments in 3D printable composite materials
TL;DR: In this article, a review covers all the recent reports in which the properties of generic 3D printable materials have been modified either by adding nanoparticles, fibers, other polymers, or by a chemical reaction for fabrication of composites with enhanced biomaterial, mechanical, electrical, thermal, optical and other properties.
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.