Recent advances in bone tissue engineering scaffolds.
TLDR
In this review, recent advances in bone scaffolds are highlighted and aspects that still need to be improved are discussed.About:
This article is published in Trends in Biotechnology.The article was published on 2012-10-01 and is currently open access. It has received 1737 citations till now. The article focuses on the topics: Bone regeneration & Tissue engineering.read more
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Fabrication and characterization of polylactic acid/polycaprolactone composite macroporous micro-nanofiber scaffolds by phase separation
TL;DR: In this article, a series of biodegradable polylactic acid (PLA)/polycaprolactone (PCL) composite micro-nanofiber scaffolds with different PCL contents (0-50 wt%) were prepared by phase separation, and the results showed that the addition of PCL had a great effect on the morphology of composite scaffolds and also changed the thermal properties and crystallinity of the PLA matrix.
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Systematic Review of Silk Scaffolds in Musculoskeletal Tissue Engineering Applications in the Recent Decade.
Li Zhang,Wei Zhang,Yejun Hu,Yang Fei,Haoyang Liu,Zizhan Huang,Canlong Wang,Dengfeng Ruan,Boon Chin Heng,Weishan Chen,Weiliang Shen +10 more
TL;DR: In this paper, a comprehensive review of the latest research on silk scaffolds in musculoskeletal tissue engineering applications is presented, which includes a comprehensive translational research route for silk biomaterial from bench to bedside.
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Osteogenic potential of Rosuvastatin immobilized on silk fibroin nanofibers using argon plasma treatment.
TL;DR: The results support the potential of plasma treatment on sustained release of the RSV from SF nanofibers for osteogenesis enhancement and the effect of plasma exposure times on the morphology, loading efficiency, release profile, and osteogenesis activity.
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Tunable Microgel‐Templated Porogel (MTP) Bioink for 3D Bioprinting Applications
TL;DR: A microgel‐templated porogel (MTP) bioink platform is reported to introduce controlled microporosity in 3D bioprinted hydrogels in the presence of living cells, providing a facile strategy to engineer precise micropores in3D printed structures to compensate for the limited resolution of current biop printing approaches.
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A Modified Polysaccharide-Based Hydrogel for Enhanced Osteogenic Maturation and Mineralization Independent of Differentiation Factors.
Sridhar Sanyasi,Satish Kumar,Arijit Ghosh,Rakesh Kumar Majhi,Navneet Kaur,Priyanka Choudhury,Udai P. Singh,Chandan Goswami,Luna Goswami +8 more
TL;DR: It is suggested that TKP-AA can potentially be used as a scaffold for diverse cell types and particularly for bone tissue engineering at low cost.
References
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Porosity of 3D biomaterial scaffolds and osteogenesis.
TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Bioceramics: From Concept to Clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article
Bioceramics : from concept to clinic
TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
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Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering
TL;DR: Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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The Extracellular Matrix: Not Just Pretty Fibrils
TL;DR: The extracellular matrix and ECM proteins are important in phenomena as diverse as developmental patterning, stem cell niches, cancer, and genetic diseases and these properties need to be incorporated into considerations of the functions of the ECM.