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Open AccessJournal ArticleDOI

Structure, function and diversity of the healthy human microbiome

Curtis Huttenhower, +253 more
- 14 Jun 2012 - 
- Vol. 486, Iss: 7402, pp 207-214
TLDR
The Human Microbiome Project Consortium reported the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome as discussed by the authors.
Abstract
The Human Microbiome Project Consortium reports the first results of their analysis of microbial communities from distinct, clinically relevant body habitats in a human cohort; the insights into the microbial communities of a healthy population lay foundations for future exploration of the epidemiology, ecology and translational applications of the human microbiome.

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Global chemical analysis of biology by mass spectrometry

TL;DR: In a recent review as mentioned in this paper, the authors discuss the informatics and hardware tools available for small-molecule analysis and provide an overview of the tools that could transform how we study the chemistry of biological systems; perhaps in the future this will be as easy as taking a photograph with a smartphone.
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The microbiota and microbiome in pancreatic cancer: more influential than expected.

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Exercise training modifies gut microbiota in normal and diabetic mice

TL;DR: Cecal microbiota from type 2 diabetic (db/db) and control (db/+) mice was obtained following 6 weeks of sedentary or exercise activity qPCR analysis revealed a main effect of exercise, with greate
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Intestinal Microbiota and Celiac Disease: Cause, Consequence or Co-Evolution?

TL;DR: The current knowledge of host-microbe interactions and how host genetics/epigenetics and environmental factors shape gut microbiota and may influence disease risk is reviewed.
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It’s the song, not the singer: an exploration of holobiosis and evolutionary theory

TL;DR: This model addresses other multi-species collectively beneficial interactions, such as biofilms or biogeochemical cycles maintaining all life, and proposes casting metabolic and developmental interaction patterns, rather than the taxa responsible for them, as units of selection.
References
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Journal ArticleDOI

A core gut microbiome in obese and lean twins

TL;DR: The faecal microbial communities of adult female monozygotic and dizygotic twin pairs concordant for leanness or obesity, and their mothers are characterized to address how host genotype, environmental exposure and host adiposity influence the gut microbiome.
Journal ArticleDOI

Vaginal microbiome of reproductive-age women

TL;DR: The inherent differences within and between women in different ethnic groups strongly argues for a more refined definition of the kinds of bacterial communities normally found in healthy women and the need to appreciate differences between individuals so they can be taken into account in risk assessment and disease diagnosis.
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