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Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Hollow gold nanoshells-incorporated injectable genetically engineered hydrogel for sustained chemo-photothermal therapy of tumor
Rui-Mei Jin,Jie Yang,Dong-Hui Zhao,Xiao-Lin Hou,Chao-Qing Li,Wei Chen,Yuan-Di Zhao,Zhong-yuan Yin,Bo Liu +8 more
TL;DR: In both in vitro cell and in vivo tumor-bearing mice experiments, a remarkably enhance tumor inhibition was observed by the combined therapy of chemo-photothermal therapy compared with photothermal therapy or chemotherapy alone.
Journal ArticleDOI
Preparation and Release Properties of a pH-Tunable Carboxymethyl Cellulose Hydrogel/Methylene Blue Host/Guest Model
TL;DR: In this article, carboxymethyl cellulose hydrogel beads were prepared in spherical form by a suspension-crosslinking technique with epichlorohydrin as a crosslinking agent and fluid wax as the suspending solvent.
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Chitosan gel formulations containing egg yolk oil and epidermal growth factor for dermal burn treatment
Evrim Yenilmez,Ebru Başaran,Rana Arslan,Murat Sami Berkman,Umay Merve Güven,C. Baycu,Yasemin Yazan +6 more
TL;DR: Chitosan based gel formulations containing Egg Yolk Oil (E1), EYO and EGF (M1) formulations seem to be better alternatives for Silverdin with a significant difference (p < 0.05) considering healing ranks of tissue samples.
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Thermosensitive Chitosan- β-Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications
TL;DR: In this article, the authors investigated a kind of temperature-sensitive smart hydrogel, which has a liquid form at room temperature and becomes gel with increasing temperature, and investigated the various factors that influence the gelation mechanism, such as gel formation rates, temperature, pH, time, and gel specificity.
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Modified nanoprecipitation method for polysulfone nanoparticles preparation
TL;DR: A modified nanoprecipitation method appending a quenching step was proposed, showing advantages including expanding the adaptability to more functional polymers, providing better flexibility on process or product development independent of the use of surfactant, and presenting a high throughput and easy-to-scale-up equipment platform.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.