Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Physical Approaches to Masking Bitter Taste: Lessons from Food and Pharmaceuticals
John N. Coupland,John E. Hayes +1 more
TL;DR: In this review, food and pharmaceutical manufacturers share a common need for bitterness-masking strategies that allow them to deliver useful quantities of the active compounds in an acceptable form and the challenges and approaches by researchers in both fields are compared.
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Stability, Intracellular Delivery, and Release of siRNA from Chitosan Nanoparticles Using Different Cross-Linkers.
TL;DR: The results demonstrate that ionically cross-linked CS-TPP nanoparticles are biocompatible non-viral gene delivery system and generate a solid ground for further optimization studies, for example with regard to steric stabilization and targeting.
Journal ArticleDOI
Photoactivated platinum-based anticancer drugs
TL;DR: The selective photoactivation of these photolabile azido-based Pt(IV) prodrugs has dramatically opened up new avenues of research aimed at overcoming the problems associated with chemotherapeutic drug delivery by incorporating different polymers, biological target molecules, permeation enhancers or nanoparticles.
Journal ArticleDOI
Graphene oxide-based hydrogels as a nanocarrier for anticancer drug delivery
Abdullah A. Ghawanmeh,Gomaa A.M. Ali,Gomaa A.M. Ali,Hamed Algarni,Hamed Algarni,Shaheen M. Sarkar,Kwok Feng Chong +6 more
TL;DR: It is anticipated that this review can stimulate a new research gateway to facilitate the development of anticancer drug delivery by harnessing the unique properties of GO based hydrogels, such as large surface area, chemical purity, high loading capacity of drug, chemical stability, and the nature of lipophilic for cell membrane penetration.
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Polymeric Scaffolds for Regenerative Medicine
TL;DR: This review focuses on polymeric scaffolds, a highly promising regenerative medicine strategy, summarizing some important issues related to various natural and synthetic scaffolding biomaterials, techniques on the design and fabrication of three-dimensional polymer scaffolds to mimic the properties of the extracellular matrix, and clinical applications of polyMER scaffolds for tissue regeneration.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.