Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Hydrogel: Preparation, characterization, and applications: A review
TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
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Chitosan-based hydrogels for controlled, localized drug delivery
TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
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Biomedical applications of hydrogels: A review of patents and commercial products
TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
References
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DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method.
TL;DR: The biological efficiency of the DNA delivery by this nano-carrier was demonstrated by an in vitro transfection assay using four cell lines, and well-defined spherical particle morphologies were demonstrated.
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Molecularly imprinted soluble nanogels as a peroxidase-like catalyst in the oxidation reaction of homovanillic acid under aqueous conditions
TL;DR: In this paper, a novel type of soluble peroxidase-like imprinted nanogels incorporating hemin, acrylamide and 4-vinylpyridine as functional monomers was prepared by solution polymerization method.
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pH-sensitive behavior of two-component hydrogels composed of N,O-carboxymethyl chitosan and alginate.
TL;DR: The results indicated that the swelling behaviors and drug-release profiles of these test hydrogels are significantly different due to their distinct cross-linking structures.
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Synthesis and in situ atomic force microscopy characterization of temperature-responsive hydrogels based on poly(2-(dimethylamino)ethyl methacrylate) prepared by atom transfer radical polymerization.
Jinyu Huang,Brian Cusick,Joanna Pietrasik,Li Wang,Tomasz Kowalewski,Qiao Lin,Krzysztof Matyjaszewski +6 more
TL;DR: Well-defined copolymers of DMAEMA and BPMA with different compositions were synthesized via atom transfer radical polymerization and the thermoresponsive behavior of the patterned polymer gel was quantitatively investigated by variable temperature in situ contact mode atomic force microscopy.
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Synthesis of alginic acid-poly[2-(diethylamino)ethyl methacrylate] monodispersed nanoparticles by a polymer-monomer pair reaction system.
TL;DR: Alginic acid-poly(2-(diethylamino)ethyl methacrylate) (ALG-PDEA) nanoparticles were successfully prepared in aqueous medium using a polymer-monomer pair reaction system, taking into account that the preparation procedure is simple, mild, and organic solvent- and surfactant-free.