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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Nanostructured hyaluronic acid-based materials for active delivery to cancer

TL;DR: To make HA useful as an intravenous targeting carrier, strategies have to be devised to reduce HA clearance from the blood; suppress the HA uptake by liver and spleen; and provide tumor-triggered mechanisms of release of an active drug from the HA carrier.
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Noncovalent encapsulation stabilities in supramolecular nanoassemblies.

TL;DR: A fluorescence resonance energy transfer (FRET) based method is described to evaluate guest exchange dynamics in the aqueous phase to analyze the stability of encapsulation in polymeric nanogels and other related amphiphilic nanoassemblies.
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Material properties of biofilms—a review of methods for understanding permeability and mechanics

TL;DR: The reader is offered a guide to current technologies that can be utilized to specifically assess the permeability and mechanical properties of the biofilm matrix and its interacting components.
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Thermoresponsive polymers: insights into decisive hydrogel characteristics, mechanisms of gelation, and promising biomedical applications.

TL;DR: The main types of thermoresponsive polymers are reviewed, with special focus on decisive hydrogel characteristics, mechanisms of gelation, and biocompatibility, and promising biomedical applications are described.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI

Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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