Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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mPEG-co-PCL nanoparticles: The influence of hydrophobic segment on methotrexate drug delivery
Rodolfo Debone Piazza,João Victor Brandt,Graciely Gomides Gobo,Antonio Claudio Tedesco,Fernando Lucas Primo,Rodrigo Fernando Costa Marques,Miguel Jafelicci Junior +6 more
TL;DR: In this article, polyethylene glycol monomethyl ether (mPEG-co-PCL) copolymer was synthesized by ring opening polymerization of the e-caprolactone in the presence of mPEG as a macroinitiator and tin(II) 2-ethylhexanoate (Sn (Oct)2), as a catalyst.
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Nanotechnology based blended chitosan-pectin hybrid for safe and efficient consolidative antiemetic and neuro-protective effect of meclizine hydrochloride in chemotherapy induced emesis
TL;DR: The developed formulation ameliorated all behavioral, biochemical and histopathological changes induced by cyclophosphamide and can offer an auspicious medication for treating distressing symptoms associated with chemotherapy for cancer patients.
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Polymeric nanoparticles loaded with the 3,5,3'-triiodothyroacetic acid (Triac), a thyroid hormone: factorial design, characterization, and release kinetics.
Karen C. dos Santos,Maria Fatima Gf da Silva,Edenir Rodrigues Pereira-Filho,João B. Fernandes,Igor Polikarpov,Moacir Rossi Forim +5 more
TL;DR: The prepared nanoparticles described here may be of clinical importance in delivering Triac for thyroid treatment and show various release rates indicating an interaction between Triac and other formulation compounds such as polymer and/or oil quantity.
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Synthesis and characterization of iron-PVA hydrogel microspheres and their use in the arsenic (V) removal from aqueous solution
Armindo Santos,Felipe Wallysson Ferreira de Oliveira,Francisco Henrique Araujo Silva,Daniel Andrada Maria,José D. Ardisson,Waldemar A. A. Macedo,Helena Eugênia Leonhardt Palmieri,Milton Batista Franco +7 more
TL;DR: In this paper, the sol-gel process was used to synthesize monodisperse metallic iron (80-155mm), iron oxide (117-200mm), xerogel (130-224mm), and -PVA hydrogel (300-600mm) microspheres.
Journal ArticleDOI
Colloidal chitin nanogels: A plethora of applications under one shell
TL;DR: Property, preparation techniques and applications of CNGs, a relatively new class of natural polymeric nanomaterials which have a large potential in the field of drug delivery and nanotherapeutics, are described.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.