Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
Reads0
Chats0
TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
More filters
Journal ArticleDOI
Laccase-mediated formation of mesoporous silica nanoparticle based redox stimuli-responsive hybrid nanogels as a multifunctional nanotheranostic agent
TL;DR: This work designed a new hybrid nanogel with redox responsive polymer gel shells and mesoporous silica nanoparticles (MSNs) cores via laccase-mediated radical polymerization that had a significantly higher cumulative DOX release in a reductive environment than that found under physiological conditions.
Journal ArticleDOI
Polyethylenimine-Based Nanogels for Biomedical Applications
TL;DR: The recent progresses in the design of PEI-based NGs for gene and drug delivery and for bioimaging applications with a target focus to tackle the diagnosis and therapy of cancer are reported.
Journal ArticleDOI
Development and characterization of mucoadhesive buccal gels containing lipid nanoparticles of ibuprofen
Ana Camila Marques,Ana Isabel Rocha,Paula Montes Leal,Marilene Estanqueiro,José Manuel Sousa Lobo +4 more
TL;DR: The incorporation of NLC in hydrogels of mucoadhesive polymers resulted in preparations with desirable rheological features as well as texture, which could benefit the therapeutic efficacy, by increasing the residence time and easiness for topical application in the buccal mucosa.
Journal ArticleDOI
Hydrogels for Advanced Stem Cell Therapies: A Biomimetic Materials Approach for Enhancing Natural Tissue Function
TL;DR: The capability of hydrogels to either enhance the function of the transplanted stem cells by promoting their controlled differentiation or enhance the recruitment of endogenous adult stem cells to the injury site for repair is reviewed.
Journal ArticleDOI
Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy.
TL;DR: This review provides a reference for the design and preparation of polysaccharide-based DDSs with excellent performance and elaborates their applications from strategic design to cancer therapy.
References
More filters
Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
Journal ArticleDOI
Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.