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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Nanocomposite hydrogel from grafting of acrylamide onto HPMC using sodium montmorillonite nanoclay and removal of crystal violet dye

TL;DR: In this paper, the effect of nanoclay content on the swelling of nanocomposites was investigated and an optimum swelling capacity was obtained at 12.7% of Na-MMt.
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Interpenetrating polymer networks hydrogels of chitosan and poly(2-hydroxyethyl methacrylate) for controlled release of quetiapine

TL;DR: In this paper, the FTIR spectra confirmed cross-linking of chitosan and polymerization of 2-hydroxyethyl methacrylate (HEMA) and showed that the materials obtained are amorphous and interpenetrated.
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Development and in vitro evaluation of lipid nanoparticle-based dressings for topical treatment of chronic wounds.

TL;DR: It is concluded that, because of their potentially longer-term stability, the fibrin-based scaffolds may be the most suitable approach to formulate rhEGF-loaded lipid nanoparticles.
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Self-assembled nanogel made of mannan: synthesis and characterization.

TL;DR: Cryo-FESEM micrographs revealed that mannan-C(16) formed irregular spherical macromolecular micelles, in this work designated as nanogels, with diameters ranging between 100 and 500 nm, which varied to some extent but was always in the nanoscale range.
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Recent advances in the structure, synthesis, and applications of natural polymeric hydrogels.

TL;DR: In this paper, the available literature related to the design concepts, types, functionalities, and applications of hydrogels with special emphasis on food applications was reviewed with a focus on the food applications.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI

Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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