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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Disulfide cross-linked nanospheres from sodium alginate derivative for inflammatory bowel disease: Preparation, characterization, and in vitro drug release behavior

TL;DR: The size of the nanospheres increased because of the cleavage of disulfides within their network structures in 10 mM glutathione (GSH) solution, and the drug release in pH 6.0 buffer with GSH from drug-loaded nanosphere exhibited a marked increase, indicating that the Nanospheres may be used for colon-specific drug delivery.
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Nanospheres of alginate prepared through w/o emulsification and internal gelation with nanoparticles of CaCO3

TL;DR: In this article, a single step technique involving emulsification and gelation of alginate spheres is described, where CaCO 3 nanoparticles, together with glucono delta-lactone (GDL), are dispersed in an alginates solution, which is subsequently dispersed in a oil phase and followed by gelation.
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Synthesis and characterization of novel dual-responsive nanogels and their application as drug delivery systems

TL;DR: The results indicated that such PNMP nanogels might have potential applications in drug delivery and other medical applications, but that the drug loading mechanism must be further developed.
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Hydrogels for ocular drug delivery and tissue engineering.

TL;DR: The potential of hydrogels in prolonged intraocular drug delivery and ocular surface therapy using stem cells incorporated hydrogELs is highlighted.
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Black phosphorus-based 2D materials for bone therapy

TL;DR: This review will first introduce the source, physicochemical properties, and degradation products of BP, then introduce the remodeling process of bone, and comprehensively summarize the progress of BP-based materials for bone therapy in the form of hydrogels, polymer membranes, microspheres, and three-dimensional (3D) printed scaffolds.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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