Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting.
Aaron C. Anselmo,Mengwen Zhang,Sunny Kumar,Douglas R. Vogus,Stefano Menegatti,Matthew E. Helgeson,Samir Mitragotri +6 more
TL;DR: Tuning nanoparticle elasticity potentially offers a method to improve the biological fate of nanoparticles by offering enhanced circulation, reduced immune system uptake, and improved targeting.
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Biopolymer-based microgels/nanogels for drug delivery applications
TL;DR: Polysaccharide-based microgels/nanogels have high water content, functionality, biocompatibility, tunable size from submicrons to tens of nanometers, large surface area for multivalent bioconjugation, and interior network for the incorporation of therapeutics.
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Photoresponsive hydrogels for biomedical applications.
TL;DR: Recent developments in photoresponsive hydrogels are reviewed and these new materials are discussed, and their applications in the biomedical field are discussed.
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Polymeric nanoparticulate system: a potential approach for ocular drug delivery.
TL;DR: DNPs have been shown to be amenable to targeting of the drug to the site of action, leading to a decreases in the dose required and a decrease in side effects, which makes them a novel polymeric drug delivery device, which fulfils the requirements for ophthalmic application.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications
TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.