Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Hydrogel: Preparation, characterization, and applications: A review
TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
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Chitosan-based hydrogels for controlled, localized drug delivery
TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
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Biomedical applications of hydrogels: A review of patents and commercial products
TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
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Chitosan for mucosal vaccination
TL;DR: It has been shown that ovalbumin loaded chitosan microparticles are taken up by the Peyer's patches of the gut associated lymphoid tissue (GALT), which demonstrates that chitOSan particulate drug carrier systems are promising candidates for oral vaccination.
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Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines.
TL;DR: It is concluded that trimethylated chitosan-DNA complexes present suitable characteristics and the potential to be used as gene delivery vectors and quaternized chitan oligomers proved to be superior to DOTAP.
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Molecular design of biodegradable polymeric micelles for temperature-responsive drug release
Masamichi Nakayama,Teruo Okano,Takanari Miyazaki,Fukashi Kohori,Kiyotaka Sakai,Masayuki Yokoyama +5 more
TL;DR: One polymeric micelle composition successfully exhibited rapid and thermo-responsive drug release while possessing a biodegradable character.
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Hydrogels for pharmaceutical and biomedical applications.
TL;DR: This review discusses various parameters of hydrogels such as surface properties, water content and swelling behavior, effect of nature of polymer, ionic content, and thermodynamics, all of which can influence the biomedical usage of Hydrogels.
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A thermosensitive hydrogel based on quaternized chitosan and poly(ethylene glycol) for nasal drug delivery system
TL;DR: Results showed that HTCC-PEG-GP formulation can be used as nasal drug delivery system to improve the absorption of hydrophilic macromolecular drugs.