Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Chitosan-based multifunctional nanomedicines and theranostics for targeted therapy of cancer.
Marziyeh Fathi,Sima Majidi,Parham Sahandi Zangabad,Jaleh Barar,Hamid Erfan-Niya,Yadollah Omidi +5 more
TL;DR: This review will document, discuss, and provide some key insights toward design and application of miscellaneous nanoplatforms based on Chitosan as a versatile polymer in targeted imaging and therapy.
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Controlled delivery of valsartan by cross-linked polymeric matrices: Synthesis, in vitro and in vivo evaluation
TL;DR: It is concluded that highly swelling chitosan-AMPS based hydrogels were developed having pH independent swelling and pH dependent drug release properties and have great potential to be used for loading and controlled release of various therapeutic agents.
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Sulfasalazine release from alginate-N,O-carboxymethyl chitosan gel beads coated by chitosan
Moslem Tavakol,Ebrahim Vasheghani-Farahani,T. Dolatabadi-Farahani,Sameereh Hashemi-Najafabadi +3 more
TL;DR: In this article, spherical beads were prepared from a water-soluble chitosan (N,O-carboxymethyl CHITOSAN, NOCC) and alginate with ionic gelation method.
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Impact of magnetic nanofillers in the swelling and release properties of κ-carrageenan hydrogel nanocomposites
TL;DR: In vitro release studies demonstrated the applicability of the composites in sustained drug release and demonstrated that the release rate and profile could be tailored using variable Fe3O4 nanoparticles load.
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Injectable hydrogels for ophthalmic applications.
Kai Wang,Zongchao Han +1 more
TL;DR: The properties of injectable hydrogels are introduced and their versatile application in the treatment of ophthalmic diseases, including age-related macular degeneration, cataracts, diabetic retinopathy, glaucoma, and intraocular cancers is summarized.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.