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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Hollow poly(N‐isopropylacrylamide)‐co‐poly(acrylic acid) microgels with high loading capacity for drugs

TL;DR: In vitro cell experiments, the drug-loaded microgels can be taken up by LoVo cells and release their payload in cell cytoplasm without loss of drug efficacy, indicating that PNIPAm-co-PAA microgelt might be a potential drug delivery carriers especially for water-soluble or polypeptide drugs.
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A novel dual-structure, self-healable, polysaccharide based hybrid nanogel for biomedical uses

TL;DR: A new unique dual-structure hydrogel composed of nanostructures of amphiphilic chitosan dispersed in a sodium alginate matrix (SAL) is presented, which has not been previously reported.
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Controlled drug delivery from mesoporous silica using a pH-response release system

TL;DR: A method for functionalizing the surface of the porous silica nanoparticles in a well-defined manner is described for controlled release of a model drug under acidic pH conditions.
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Thermoplastic Vinyl Polymers: From Macro to Nanostructure

TL;DR: In this article, a structural overview of synthetic thermoplastic polymers and their physicochemical characteristics, structure-property relationships, applications, and limitations are discussed. But, the authors do not provide a thorough overview of the synthetic vinyl polymer classes available.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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