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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Encapsulation of food bioactives and nutraceuticals by various chitosan-based nanocarriers

TL;DR: In this review, various approaches and techniques for development of chitosan-based nanodelivery systems with an overview of the related studies will be discussed, and nutritional and functional properties of the nanostructures and relevant safety issues are highlighted.
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Multifunctional interpenetrating polymer network hydrogels based on methacrylated alginate for the delivery of small molecule drugs and sustained release of protein.

TL;DR: The DCS and BSA release results indicated that these hydrogels have great potential for use in the oral delivery of small molecule drugs and for long-term localized protein release.
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Layer-by-Layer polyelectrolyte assemblies for encapsulation and release of active compounds.

TL;DR: This review studies different physico - chemical aspects associated with the assembly of supramolecular materials by the LbL method, paying special attention to the description of these aspects playing a central role in the application of these materials as cargo platforms for encapsulation and release of active compounds.
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Modified biopolymer-dextrin based crosslinked hydrogels: application in controlled drug delivery

TL;DR: The importance of crosslinked hydrogels in drug delivery applications and various dextrin based hydrogel used in sustained drug delivery studies have been explored, which confirm that future clinical applications of these materials in the biomedical and pharmaceutical fields are feasible.
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Nanomedicine as an emerging approach against intracellular pathogens.

TL;DR: This review will summarize, for the first time, the intracellular compartments in which pathogens can reside and discuss how nanomedicine has the potential to improve intrACEllular disease therapy by offering properties such as targeting, sustained drug release, and drug delivery to the pathogen’s intrace cellular location.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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