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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Starch‐g‐lactic acid/montmorillonite nanocomposite: Synthesis, characterization and controlled drug release study

TL;DR: In this paper, a new starch-g-lactic acid/montmorillonite nanocomposite was developed for controlled and sustained drug release for fluoxetine.
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Mechanically Strong and Thermally Responsive Cellulose Nanofibers/Poly(N-isopropylacrylamide) Composite Aerogels

TL;DR: In this paper, a cellulose nanofibers (CNFs)/poly(N-isopropylacrylamide) (PNIPAm) composite aerogels were successfully fabricated from a CNF aqueous suspension containing PNIPAm solute via lyophilization.
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A novel stimuli-responsive hydrogel for K+-induced controlled-release

TL;DR: In this article, a novel family of stimuli-responsive smart hydrogel is developed for K+ -induced self-regulated controlled-release, which is featured with isothermally K + -induced pulse-release mode at a certain temperature.
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Freeze/thawed polyvinyl alcohol hydrogels: Present, past and future

TL;DR: A comprehensive review of polyvinyl alcohol (PVA) hydrogels prepared by the freezing/thawing (F-T) process is presented in this paper , where the authors discuss their preparation, gelation mechanisms, handling of physical/mechanical properties, physicochemical characteristics, and various applications.
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Synthesis and physical gels of pH- and thermo-responsive tertiary amine methacrylate based ABA triblock copolymers and drug release studies

TL;DR: A series of pH-responsive ABA triblock copolymer gelators have been synthesized by using poly[2-(diisopropylamino)ethyl methacrylate] (PDPA) as the A block and poly[dimethylamino (ethyl methacelate) (PDMA), as the B block via group transfer polymerization as mentioned in this paper.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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