Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Morphology and mechanical properties of bicontinuous gels of agarose and gelatin and the effect of added lipid phase
TL;DR: This study examines the structural properties of binary and tertiary mixtures made of the cold-setting biopolymers agarose and gelatin and a lipid phase with solid or liquid-like viscoelasticity to find an unexpected outcome that contradicts the central finding.
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Poly (N‐isopropylacrylamide) microgel‐based assemblies
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Biodegradable Ingredient-Based Emulgel Loaded with Ketoprofen Nanoparticles
TL;DR: Nanoparticle-loaded argan oil emulgel significantly enhanced skin penetration of ketoprofen as compared to marketed gel, and prepared successfully delivered drug through transdermal route using natural ingredients.
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Synthesis and characterization of thiolated carboxymethyl chitosan-graft-cyclodextrin nanoparticles as a drug delivery vehicle for albendazole.
Ghazaleh Alamdarnejad,Alireza Sharif,Shahrouz Taranejoo,Mohsen Janmaleki,Mohammadreza Kalaee,Mohsen Dadgar,Mazyar Khakpour +6 more
TL;DR: It was found that the thiolated carboxymethyl chitosan-g-cyclodextrin nanoparticles prepared using an aqueous solution containing 1 wt% of tripolyphosphate and having 115.65 (μmol/g polymer) of grafted thiol groups show both the highest mucoadhesive properties and the highest albendazole entrapment efficiency.
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Physiologically relevant, pH-responsive PEG-based block and statistical copolymers with N,N-diisopropylamine units
Annabelle Lee,Pontus Lundberg,Daniel Klinger,Bongjae F. Lee,Craig J. Hawker,Nathaniel A. Lynd +5 more
TL;DR: It was demonstrated that DEGE containing copolymers could serve as building blocks for the formation of new pH-responsive materials with a pKa of ca.
References
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Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.