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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Hydrogel: Preparation, characterization, and applications: A review

TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
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Chitosan-based hydrogels for controlled, localized drug delivery

TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
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Biomedical applications of hydrogels: A review of patents and commercial products

TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy

TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy

TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
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Journal Article

Dynamic pH-dependent swelling properties of a hydrophobic polyelectrolyte gel

TL;DR: Copolymere methacrylate de methyle/methacelate de N,N-dimethylaminoethyle obtenu en presence d'une petite quantite de divinyl-benzene as discussed by the authors.
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Novel silica-biopolymer nanocomposites : the silica sol-gel process in biopolymer organogels

TL;DR: In this paper, a novel sol-gel nanocomposite material is introduced which was produced by silica solgel processes in micro-emulsion organogels, where the oxid gel forms an interpenetrating network with the gelatin maze.
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Targeted delivery of arjunglucoside I using surface hydrophilic and hydrophobic nanocarriers to combat experimental leishmaniasis

TL;DR: It was apparent that in addition to a smaller size and better drug release profile, the contribution of other parameters, e.g. overall surface hydrophilicity or hydrophobicity of the vehicles, also play an important role in the macrophage uptake of the drug.
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pH- and Thermo-sensitive Hydrogel Nanoparticles☆

TL;DR: Hydrogel nanoparticles of copolymers of vinylpyrrolidone and acrylic acid cross-linked with NN' methylene bis acrylamide and FITC-dextran have high entrapment efficiency and can be redissolved in buffer without any significant agglomeration.
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Synthesis, characterization, and biomedical applications of core–shell-type stimuli-responsive nanogels – Nanogel composed of poly[2-(N,N-diethylamino)ethyl methacrylate] core and PEG tethered chains

TL;DR: PEGylated nanogels show unique properties and functions in synchronizing with the reversible volume phase transition of the PDEAMA core in response to various stimuli, such as pH, ionic strength and temperature.
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