Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Applications of nanocomposite hydrogels for biomedical engineering and environmental protection
Gaurav Sharma,Bharti Thakur,Mu. Naushad,Amit Kumar,Florian J. Stadler,Sulaiman M. Alfadul,Genene Tessema Mola +6 more
TL;DR: Nanocomposite hydrogels have special characteristics such as high swelling rate, selectivity and stimuli-sensitive nature and are therefore good bio-absorbent materials for environmental detoxification and biomedical engineering.
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Stimuli-responsive microgels for the loading and release of functional compounds: Fundamental concepts and applications
TL;DR: A broad overview of the design criteria and practical methodologies to control the functionality of microgels is presented in order to encourage further development of highly interesting concepts and materials in this area of materials science.
Journal ArticleDOI
Revisiting structure-property relationship of pH-responsive polymers for drug delivery applications.
Salime Bazban-Shotorbani,Mohammad Mahdi Hasani-Sadrabadi,Mohammad Mahdi Hasani-Sadrabadi,Akbar Karkhaneh,Vahid Serpooshan,Karl I. Jacob,Alireza Moshaverinia,Morteza Mahmoudi,Morteza Mahmoudi +8 more
TL;DR: The pH variations in the body at the organ level, tissue level, and cellular level are correlated with the intrinsic properties of pH‐responsive polymers, which could help to select more effective (‘smart’) polymeric systems based on the biological target.
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Multi-responsive nanogels containing motifs of ortho ester, oligo(ethylene glycol) and disulfide linkage as carriers of hydrophobic anti-cancer drugs.
TL;DR: The results indicate that the volume phase transition temperature (VPTT), thermally induced deswelling ratio, and acid-triggered swelling ratio of the nanogels are closely relevant to their compositions and crosslinking degrees.
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Therapeutic cell delivery and fate control in hydrogels and hydrogel hybrids
TL;DR: The development of strategies aiming to overcome the aforementioned two 'shortcomings' by establishing ADC survival and creating space for tissue formation respectively are reviewed, and how people take advantage of these 'disadvantages' of hydrogel encapsulation for an enhanced confinement of cell motion is introduced.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.