Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Encapsulation of Hydrophobic Phthalocyanine with Poly( N -isopropylacrylamide)/Lipid Composite Microspheres for Thermo-Responsive Release and Photodynamic Therapy.
Jiaojiao Liu,Jingliang Li,Zexin Zhang,Yuyan Weng,Gaojian Chen,Bing Yuan,Kai Yang,Yu-qiang Ma +7 more
TL;DR: This work efficiently encapsulate Pc into poly(N-isopropylacrylamide) microgel particles, without or with lipid decoration, to improve its water solubility and prevent aggregation in aqueous medium and demonstrates promising candidates in promoting the use of hydrophobic drugs including photosensitizers in tumor therapies.
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Oral delivery of chemotherapeutic agents: background and potential of drug delivery systems for colon delivery
TL;DR: It is believed that using physiological cues and environments of the gastrointestinal tract and designing smart polymer carriers, the quest for oral drug delivery of chemotherapeutics may be achieved.
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Can self-assembled hydrogels composed of aromatic amino acid derivatives function as drug delivery carriers?
Priyanka Tiwari,Ramanathan Rajagopalan,Mohammad Moin,Rohit Soni,Piyush Trivedi,Anita DuttKonar +5 more
TL;DR: Two simple N-terminally protected aromatic amino-acid derivatives that form efficient stable hydrogels at room temperature are synthesized to explore the efficacy of the hydrogel nanoparticles as tools for drug delivery and shed some light on the candidature of these novel types of aromatic amino acid hydrogeling for nano-medical applications.
Journal ArticleDOI
Highly hydrated poly(allylamine)/silica magnetic resin
Andrew K. Johnson,Jozef Kaczor,H. Han,Maninder Kaur,Guoxin Tian,Linfeng Rao,You Qiang,Andrzej Paszczynski +7 more
TL;DR: In this paper, the magnetic nanoparticles (MNPs) with 50 nm average size were used (size distribution from 20 to 100 nm and an iron content of 80-90 w/w%).
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A network composed of gold nanoparticles and a poly(vinyl alcohol) hydrogel for colorimetric determination of ceftriaxone
Nahid Pourreza,Matineh Ghomi +1 more
TL;DR: A hydrogel network was prepared from poly(vinyl alcohol) (PVA) and borax, and then was modified with gold nanoparticles (AuNPs) that were obtained by in-situ nucleation and growth to be a viable optical nanoprobe for the drug ceftriaxone (CTRX) in biological samples.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.